GENETIC ANALYSIS OF ATHEROSCLEROSIS SUSCEPTIBILITY IN THE MOUSE
J.L. Breslow, USA

A SYSTEMS BIOLOGY APPROACH TO THE METABOLIC SYNDROME
J. Scott, T. Aitman, Y. Guo, R. Naoumova, J. Nicholson, C. Shoulders, UK

GUIDELINES FOR THE PREVENTION OF ATHEROSCLEROTIC DISEASES. A EUROPEAN VIEW
O. Faergeman, Denmark

NCEP GUIDELINES AND THE AMERICAN POINT OF VIEW
F.M. Sacks, USA

Coffee Break, Poster Viewing and Exhibition Visit

GENE-ENVIRONMENT INTERACTION IN CORONARY ARTERY DISEASE (CAD)
S.E. Humphries, UK

A LDLR GENOMIC SCREENING STRATEGY REVEALS NOVEL AND SPLICING REGULATORY MUTATIONS CAUSING FAMILIAL HYPERCHOLESTEROLEMIA
S. Amsellem, D. Briffaut, A. Carrie, J.P. Rabes,J.P. Girardet, A. Fredenrich,
P. Moulin, M. Krempf, Y. Reznik, B. Vialettes, J.L. De Gennes, E. Bruckert,
P. Benlian, France

HEME OXYGENASE-1 GENOTYPE AND RESTENOSIS AFTER FEMOROPOPLITEAL PTA: A NOVEL VASCULAR PROTECTIVE FACTOR
M. Exner , M. Schillinger, E. Minar, W. Mlekusch, M. Muellner, C. Mannhalter,
F.H. Bach, O. Wagner, Austria, USA

THE APOLIPOPROTEIN A-V GENE PREDISPOSES TO HIGH PLASMA TRIGLYCERIDES IN FAMILIAL COMBINED HYPERLIPIDEMIA
J. Ribalta, L. Figuera, J. Fernandez-Ballart, E. Vilella, M. Castro Cabezas,
J. Joven, Spain, The Netherlands

CARDIOVASCULAR RISK MARKERS IN AN OVERWEIGHT AND NORMAL WEIGHT POPULATION WITH OVERSAMPLING OF CARRIERS OF THE IRS-1 972ARG VARIANT
A. Jellema, E.J.M. Feskens, R.P. Mensink, W.H.M. Saris, D. Kromhout,
The Netherlands

THE 5A/6A STROMELYSIN POLYMORPHISM AND ECHOGENIC PLAQUES: DEWSBURY AND MAIDSTONE PART OF THE BRITISH REGIONAL HEART STUDY
E. Bashiardes, M. Cariolou, M. Giffin, A. Nicolaidis, A. Karagrigoriou,
S. Ebrahim, S.E. Humphries, Cyprus, UK

THE IN VIVO IMPORTANCE OF SR-BI AND ABCA1 FOR THE DEVELOPMENT OF ATHEROSCLEROTIC LESIONS AND REVERSE CHOLESTEROL TRANSPORT
T. Van Berkel, J. Spijkers, R. Out, M. Hoekstra, J. Twisk, M. Van Eck,
The Netherlands

REVERSE CHOLESTEROL TRANSPORT IN VIVO
O. Stein, Y. Stein, Israel

ROLES OF ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1) AND SCAVENGER RECEPTOR BI (SR-BI) DURING APOA-1 AND HDL DEPENDENT STEROL FLUX FROM CAPILLARY ENDOTHELIAL CELLS OF THE BLOOD-BRAIN BARRIER
U. Panzenboeck, Z. Balazs, A. Wintersperger, A. Hrzenjak, G.M. Kostner,
W. Sattler, Austria

PROBUCOL INHIBITION OF ABCA1-MEDIATED CELLULAR LIPID EFFLUX
E. Favari, F. Bernini, G.H. Rothblat, G. Kellner-Weibel, Italy, USA

HETEROZYGOSITY FOR ABCA1 GENE MUTATIONS: EFFECTS ON LIPID METABOLISM
J.A. Kuivenhoven, G.K. Hovingh, A. Van Tol, A.H. Smelt, J.C. Fruchart,
E. Brinton, J.D. Olvos, A.H. Zwinderman, M.R. Hayden, J.J.P. Kastelein,
The Netherlands

LIPASES AND LIPOPROTEIN METABOLISM: INSIGHTS FROM TRANSGENIC MICE
R. Zechner, Austria

FUNCTION OF LIPASES IN LIPOPROTEIN UPTAKE - A PHYSIOLOGICALLY RELEVANT PROCESS
U. Beisiegel, Germany

THE LDL RECEPTOR MEDIATES LPL ENHANCED LDL UPTAKE BUT NOT CHYLOMICRON UPTAKE INTO THE MUSCLE IN MICE
M. Merkel, J. Heeren, M. Blaeser, K. Frahm, H. Greten, Germany

UPTAKE INTO HEPG2 CELLS
J.G. Strauss, M. Hayn, R. Zechner, S. Frank, Austria

ATHEROGENICITY OF LIPOPROTEIN LIPASE IN TRANSGENIC RABBITS
J. Fan, T. Ichikawa, H. Unoki, J. Liang, T. Koike, S. Kitajima, T. Watanabe,
Japan

LOW HEPATIC LIPASE ACTIVITY IS A NOVEL RISK FACTOR FOR CORONARY ARTERY DISEASE
K.A. Dugi, K. Brandauer, N. Schmidt, B. Nau, J.G. Schneider, S. Mentz,
T. Keiper, J.R. Schaefer, M.L. Bahner, J. Kreuzer, Germany

XIAP MEDIATES CELL-CYCLE ARREST AND ACTIVATES NF-KB: NEW SURVIVAL PATHWAYS AND THEIR DESTRUCTION BY CASPASES DURING ENDOTHELIAL APOPTOSIS
B. Levkau, K.J. Garton, N. Ferri, R.J. Nofer, H. Baba, E.W. Raines,
G. Breithardt, Germany, USA

THE IMPACT OF 12-WEEK AQUATIC EXERCISE ON LIPID AND RENAL PARAMETERS IN CHRONIC RENAL FAILURE PATIENTS
Y. Pechter, J. Maaroos, S. Mesikepp, A. Veraksits, M. Ots, Estonia

EO TRAVEL GRANT WINNER: DOES INFLAMMATION PLAY IMPORTANT ROLE IN PATHOGENESIS OF ATHEROSCLEROSIS AND ITS CLINICAL OUTCOME?
I. Burazor, M. Burazor, S. Nagorni, J. Glasnovic, V. Djordjevic, V. Cosic,
Z. Burazor, N. Burazor, Yugoslavia

CIRCULATING COLONY-FORMING UNITS FOR OSTEOCLASTS IN CORONARY PATIENTS WITH HYPERLIPIDEMIA
O.S. Saburova, T.A. Rozhkova, E.L. Soboleva, Russia

INFLUENCE OF IRBESARTAN ON PLASMA CONCENTRATIONS OF ADHESION MOLECULES AND CHEMOKINES IN CORONARY HEART DISEASE WITH DOCUMENTED CORONARY ATHEROSCLEROSIS
I.V. Korzh, Ukraine

PLTP EXPRESSION IN THE CENTRAL NERVOUS SYSTEM OF RABBITS
R. Gander, P. Eller, S. Kaser, I. Theurl, D. Walter, T. Sauper, A. Ritsch,
J.R. Patsch, B. Foeger, Austria

IDENTIFICATION OF ASYMPTOMATIC PATIENTS AT INCREASED RISK OF ACUTE CORONARY EVENTS
M.F. Carrageta, Portugal

OB-GENE PRODUCT LEPTIN IS ABLE TO INDUCE MONOCYTIC TISSUE FACTOR EXPRESSION
P. Quehenberger, Germany

A NOVEL APPROACH TO CHOLESTEROL LOWERING: LIPOPROTEIN CHARGE CONTROL
D.L. Sparks, Canada

POSSIBLE INFLUENCE OF EXTREMELY LOW FREQUENCY (ELF) ELECTROMAGNETIC RADIATION FIELDS (EMF) ON ATHEROSCLEROSIS
B.R. Henderson, G. Pfister, M. Kind, G. Boeck, G. Wick, Austria

INTIMAL RETENTION OF LIPOPROTEIN CHOLESTEROL IN CAROTID ARTERIES FROM WATANABE RABBITS
S. Proctor, J.C. Mamo, Australia

INTRODUCING A NEW MODEL FOR STUDYING MACROPHAGE HOMING INTO ATHEROSCLEROTIC PLAQUE IN APOE-DEFICIENT MICE
S. Litovsky, P.R. Wyde, M. Madjid, A. Akhtar, S.W. Casscells, M. Naghavi, USA

DISCUSSION

NON-INVASIVE DETECTION AND CHARACTERIZATION OF CORONARY ATHEROSCLEROTIC PLAQUE
U. Hoffmann, R. Chan, T. Brady, USA

NON-INVASIVE CHARACTERISATION OF CAROTID ATHEROSCLEROSIS BY ULTRASOUND
H. Sillesen, Denmark

B-MODE DETECTION OF SUBCLINICAL ATHEROSCLEROSIS
H.N. Hodis, W.J. Mack, USA

DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA IN CHILDREN
A. Wiegman, E.J.G. Sijbrands, J. Rodenburg, J.J.P. Kastelein,
The Netherlands

ABCA1 AND ATHEROSCLEROSIS: ASSESSMENT BY CHOLESTEROL EFFLUX AND IMT MEASUREMENTS
J.C. Defesche, J.J.P. Kastelein, K. Hovingh, E. De Groot, S.M. Clee,
A.H. Zwinderman, M.R. Hayden, The Netherlands, Canada

THE NADPH-OXYDASE P22PHOX C242T POLYMORPHISM IS ASSOCIATED WITH AN INCREASED RISK OF ATHEROSCLEROSIS
M. Roest, J. Defesche, J. Kastelein, R. Voorbij, The Netherlands

REGULATION OF HUMAN CETP GENE PROMOTER ACTIVITY: ROLE OF MULTIPLE BINDING SITES FOR SP1 AND SP3 TRANSCRIPTION FACTORS
W. Le Goff, M. Gu?rin, L. Petit, M.J. Chapman, J. Thillet, France

ALCOHOL INTAKE MAY NOT BE PROTECTIVE AGAINST CORONARY HEART DISEASE IN SUBJECTS WITH DEFECTIVE ALDH2 GENOTYPES
Y. Nakamura, K. Amamoto, Y. Tsujita, S. Tamaki, Y. Ueno, Y. Kita,
T. Okamura, A. Nozaki, T. Kadowaki, H. Ueshima, Japan

HDL AND OTHER FACTORS IN THE GENETICS OF ISCHEMIC HEART DISEASE
B.G. Nordestgaard, A. Tybjaerg-Hansen, Denmark

MOLECULAR MECHANISM OF CHOLESTEROL EFFLUX; INVOLVEMENT OF A MEMBER OF THE RHO GTPASE FAMILY CDC42
S. Yamashita, K-I. Hirano, K. Tsukamoto,A. Matsuyama, F. Matsuura,
M. Ishigami, N. Sakai, Y. Matsuzawa, Japan

SCAVENGER RECEPTORS PRESENT IN THE INTESTINAL BRUSH BORDER MEMBRANE MEDIATE THE TRANSPORT OF CHOLESTEROL AND OTHER DIETARY LIPIDS
H. Hauser, M. Werder, C-H. Han, G. Schulthess, Switzerland

EXOGENOUS SHORT CHAIN CERAMIDE AND SPHINGOSINE INDUCE INTRACELLULAR CERAMIDE FORMATION AND MODULATE APO AI-ABCA1 DEPENDENT LIPID EFFLUX
W. Drobnik, G. Liebisch, B. Lieser, R. Schifferer, G. Schmitz, Germany

INCREASED INTESTINAL ABCA1 EXPRESSION CONTRIBUTES TO THE DECREASE IN CHOLESTEROL ABSORPTION AFTER PLANT STANOL CONSUMPTION
J. Plat, R.P. Mensink, The Netherlands

MUTATIONS IN THE HUMAN ATP-BINDING CASSETTE TRANSPORTERS ABCG5 AND ABCG8 IN SITOSTEROLEMIA
S. Heimerl, T. Langmann, C. Moehle, R. Mauerer, M. Dean, F-U. Beil,
K. Von Bergmann, G. Schmitz, Germany, USA

VARIATION IN THE ABCA1 GENE, REVERSE CHOLESTEROL TRANSPORT, AND ATHEROSCLEROSIS IN THE POPULATION AT LARGE. THE COPENHAGEN CITY HEART STUDY
R. Frikke-Schmidt , B.G. Nordestgaard, G.B. Jensen, A. Tybjaerg-Hansen, Denmark

MECHANISM OF LCAT ACTIVATION BY APO A-I
S. Roosebeek, F. Peelman, M. Rosseneu, Belgium

THE COMPLEMENTARY ROLES OF HEPATIC LIPASE AND ENDOTHELIAL LIPASE IN HDL METABOLISM
K.A. Rye, Australia

PHOSPHOLIPID TRANSFER PROTEIN, A NOVEL PLAYER IN LIPOPROTEIN METABOLISM
A. Van Tol, The Netherlands

CLINICAL AND ANALYTICAL FEATURES OF A NEW CASE OF LCAT DEFICIENCY
P. Valdivielso, I. Garcia, P. Aranda, G. Martin, C. Garcia, M.A. Frutos,
P. Gonzalez, Spain

CHARACTERIZATION OF THE PHOSPHOLIPID TRANSFER PROTEIN (PLTP) SECRETED BY HEPG2 CELLS
S.L. Siggins, M. Jauhiainen, V. Olkkonen, C. Ehnholm, Finland

MEDITERRASIAN - THE BEST CARDIOPROTECTIVE CUISINE
D. Colquhoun, Australia

ADDITIVE EFFECT OF STEROL-ESTER MARGARINE WITH STATIN IN LOWERING LDL CHOLESTEROL IN PRIMARY HYPERCHOLESTEROLAEMIA
L.A. Simons, Australia

NUTRITIONAL FACTORS AND ATHEROSCLEROSIS: THE FACTS
K. Widhalm, Austria

MEDITERRANEAN DIET AND POST-AMI RISK OF CARDIOVASCULAR MORTALITY
R. Marchioli, F. Barzi, R.M. Marfisi, M. Woodward, Italy, Australia

THE ISOFLAVONE, BIOCHANIN, LOWERS LDL-CHOLESTEROL IN MEN
P. Nestel, H. Teede, Australia

EFFECT OF DIETARY AND ANTISMOKING ADVICE ON MORTALITY IN MEN DEPENDS ON CONCENTRATION OF TRIGLYCERIDES. A 22-YEAR FOLLOW-UP STUDY
I. Ellingsen, I. Hjermann, M. Abdelnoor, E. Hjerkinn, S. Tonstad, Norway

MEDITERRANEAN DIET, AND ITS ASSOCIATION WITH CLINICAL AND BIOCHEMICAL MARKERS RELATED TO CARDIOVASCULAR RISK: THE ATTICA STUDY
C. Chrysohoou, C. Pitsavos, J. Skoumas, D. Panagiotakos, M. Toutouza,
I. Papaioannou, A. Zeimbekis, C. Stefanadis, P. Toutouzas, Greece

FENOFIBRATE INCREASES HDL-ASSOCIATED PAF-ACETYLHYDROLASE. A NEW PLEIOTROPIC EFFECT OF FIBRIC ACID DERIVATIVES?
V. Tsimihodimos, E. Bairaktari, A. Tambaki, E. Liberopoulos, M. Elisaf,
A. Tselepis, Greece

HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: NOVEL THERAPY WITH EZETIMIBE
E. Bruckert, C. Gagne, D. Gaudet, P. Sager, D. Ponsonnet, L. Lipka,
A. LeBeaut, R. Suresh, P. Abreu, E. Veltri, France, Canada, USA

CENTRAL OBESITY, ELEVATED TRIGLYCERIDES AND LOW HIGH DENSITY LIPOPROTEIN LEVELS ARE ASSOCIATED WITH LOW DENSITY LIPOPROTEIN SIZE IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLAEMIA
H. Nawawi, K. Bador, M.R. Sara, B.A.K. Khalid, K. Yusoff, Malaysia

CLASSICAL RISK FACTORS FOR ISCHEMIC HEART DISEASE AND C-REACTIVE PROTEIN IN ACUTE CORONARY SYNDROMES
L. Bronze, J. Monge, A. Anao, J. Galvao, C. Ferreira, J. Azevedo, A. Aleixo,
Portugal

GENISTEIN INHIBITS CRP-INDUCED E-SELECTIN INDUCTION IN HUMAN AORTIC ENDOTHELIAL CELLS
M. Exner, M. Raith, B. Gmeiner, O. Wagner, S. Kapiotis, Austria

THE V249I POLYMORPHISM IN THE FRACTALKINE RECEPTOR CX3CR1 IS NOT ASSOCIATED WITH PERIPHERAL ARTERIAL DISEASE
A. Gugl, W. Renner, G. Seinost, M. Brodmann, E. Pabst, T.C. Wascher,
B. Paulweber, B. Iglseder, E. Pilger, Austria

ULTRASENSITIVE MICROSCOPY OF THE UPTAKE OF INDIVIDUAL HDL PARTICLES VIA SCAVENGER RECEPTOR CLASS B TYPE I IN LIVING CELLS
J. Hesse, M. Sonnleitner, A. Breuer, G.J. Schuetz, M. Doringer, H. Stangl,
Austria

PLATELET-MONOCYTE CROSS TALK AND TISSUE FACTOR EXPRESSION IN STABLE ANGINA VERSUS UNSTABLE ANGINA/NON-ST-ELEVATION MYOCARDIAL INFARCTION
C.W. Kopp, S. Steiner, D. Seidinger, N. Iordanova, G. Maurer, E. Minar,
K. Huber, Austria

LONG-TERM COMPLIANCE TO LIPID LOWERING MEDICATION AFTER GENETIC SCREENING FOR FAMILIAL HYPERCHOLESTEROLEMIA
M.A.W. Umans-Eckenhausen, J.C. Defesche, J.J.P. Kastelein,
The Netherlands

DISCUSSION

INFLAMMATORY ACTIVATION OF VASCULAR CELLS: CELLULAR AND MOLECULAR MECHANISMS
B.R. Binder, Austria

ROLE OF NUCLEAR RECEPTORS IN LIPOPROTEIN METABOLISM
J.C. Fruchart, France

THE EFFECT OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA2 (PPAR-G2) PRO12ALA VARIANT ON HYPERTENSION , GLUCOSE AND LIPID TOLERANCE IN THE OFFSPRINGS OF FAMILIES WITH FAMILIAR OBESITY IN SOUTH OF POLAND
A. Dembinska-Kiec, I. Wybranska, M. Malczewska-Malec,
I. Leszczynska-Golabek, B. Kiec-Wilk, A. Jabrocka, M. Kwasniak, M. Motyka,
Poland

COMPARISON OF THE EFFECT OF PPARALPHA, APO E2, LPL OR LDL-RECEPTOR GENE MUTATIONS ON THE CHOLESTEROL AND TRIGLYCERIDE CONTENT OF APOB CONTAINING LIPOPROTEINS (VLDL, IDL, LDL): IS THERE ANY CLINICAL IMPLICATION?
D. Brisson, M-C. Vohl, P. Perron, T.J. Hudson, D. Gaudet, Canada, USA

PPAR GAMMA COACTIVATOR-1 RECRUITMENT REGULATES PPAR SUBTYPE SPECIFICITY
H. Oberkofler, H. Esterbauer, V. Linnemayr, D. Strosberg, F. Krempler,
W. Patsch, Austria, France

DISCUSSION

MEMBERS OF THE PROGRAMME COMMITTEE AND THE EAS COUNCIL
G.M. Kostner
K.M. Kostner
U. Beisiegel