Poster Presentations

Thursday, March 12 – Friday, March 13 ,2009

Novel Biological Agents:

CHARACTERIZATION OF THIOREDOXIN-80 IN THE BRAIN ANT ITS RELEVANCE IN ALZHEIMER´S DISEASE
F. Gil-Bea¹, S. Akterin¹, L. Mateos¹, S. Costa¹, J. Avila-Cariño², E. Sundström³, A. Holmgren⁴, A. Cedazo-Minguez^1
1Karolinska Institutet, KI-Alzheimer´s Disease Research Center, Huddinge, Sweden, ²Karolinska Institutet, Department of Cell and Molecular Biology, Stockholm, Sweden, ³Karolinska Institutet, Division of Neurodegeneration and Neuroinflammation, Huddinge, Sweden, ⁴Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Stockholm, Sweden

ABETA CAUSES MEMORY IMPAIRMENT BY DISTURBING THE JAK2/STAT3 AXIS IN HIPPOCAMPAL NEURONS
T. Chiba, M. Yamada, S. Aiso
KEIO University, School of Medicine, Department of Anatomy, Tokyo, Japan

BENEFICIAL EFFECTS OF DIETARY SUPPLEMENTATION OF ZINC IN TRIPLE TRANSGENIC AD MICE
C. Corona, F. Mascioli, T. Caporale, S.L. Sensi
Center of Excellence on Aging, Univ. D'Annunzio Chieti-Pescara, BAMS, Chieti, Italy

A SYNTHETIC DERIVATIVE OF A TETRAHYDROISOQUINOLINE ALKALOID FROM MUCUNA PRURIENS IS NEUROPROTECTIVE IN MPTP MODEL OF PARKINSON'S DISEASE
T. Sengupta¹, J. Vinayagam², P. Jaisankar², K.P. Mohanakumar^1
1Indian Institute of Chemical Biology (CSIR), Division of Cell Biology & Physiology, Kolkata, India, ²Indian Institute of Chemical Biology (CSIR), Division of Medicinal Chemistry, Kolkata, India

MODULATION OF ALPHA SYNUCLEIN AGGREGATION BY FILAMENTOUS PHAGES IN A CELLULAR MODEL OF PARKINSON´S DISEASE
H. Dimant¹, N. Sharon², B. Solomon^2
1Tel Aviv University, Molecular Biology and Biotechnology, Tel Aviv, Israel, ²Tel Aviv University, Tel Aviv, Israel

Z-LIGUSTILIDE PROTECTS AGAINST AMYLOID B-INDUCED CYTOTOXICITY IN SH-SY5Y CELLS
J.-R. Du, Y. Yu, B. Bai
West China School of Pharmacy, Sichuan University, Chengdu, China

THE EFFECT OF SAN-61 ON BETA AMYLOID (Aβ_1-42) TOXICITY IN RAT MIXED CORTICAL CULTURES
M. Williams¹, M. Charles¹, T.-K. Stenius², A. Nurmi², N. Vartiainen², J. Yrjanheikki^2
1Sanomune Inc., Winnipeg, Canada, ²Cerebricon Ltd., Kuopio, Finland

THE KETONES β-HYDROXYBUTYRATE AND ACETOACETATE PREVENT THE INHIBITION OF HIPPOCAMPAL LONG-TERM POTENTIATION BY AMYLOID Aβ_1-42
M. Maalouf¹, K. Fehlhaber¹, M. Zhao², D. Eisenberg², F. Schweizer^1
1University of California, Neurobiology, Los Angeles, United States, ²University of California, Biological Chemistry, Los Angeles, United States