TOPICS
- ETIOLOGY AND PATHOGENESIS
- Somatic hypermutation in human autoantibodies
- Innate autoimmunity and adoptive autoimmunity
- Toll-like receptors in autoimmunity
- Apoptosis and autoimmunity
- Molecular signalling in apoptosis of T cell subsets
- Vascular injury: insights gained through proteomics and genomics
- Tracking CD4+ T cells in the pathogenesis of human autoimmune diseases
- Effectors of autoimmune tissue injury
- Autoimmune epitopes: autoepitopes
- Pathogenic mechanisms involving cytokines
- The role of interferons in the pathogenesis of lupus
- Neurotransmitters and immunology interactions
- Infections as a cause of autoimmune diseases
- Role of infection in vascular injury
- Pathogenesis of autoimmune cardiomyopathy
- Pathogenic potential of ANCA
- Tissue factor and autoimmunity
- Complement and autoimmunity
- Origins of rheumatoid arthritis
- GENETICS
- Genetics of autoimmune diseases (CD4/CD25 regulatory T cells)
- Autoimmunity predisposing genes
- Genes involved in tolerance and autoimmunity
- Gene expression in multiple sclerosis
- Express yourself! Gene expression profiling in rheumatic diseases
- Immunoglobulin gene regulation in autoimmunity
- The genetics of SLE
- Immunogenetics of autoimmune thyroid diseases
- Genome wide SNP analyses on rheumatoid arthritis
- TCR gene transfer for controlling autoimmunity
- MECHANISM
- Penetration of autoantibodies into living cells
- Role of dendritic cells in the induction of tolerance/autoimmunity
- Chemokines and their receptors in autoimmune diseases
- Cell adhesion molecules in arthritis and autoimmune diseases
- Food antigens and autoimmunity
- Environment versus genetics in autoimmunity
- Migration of autoimmune T cells
- Autoimmune B cells
- B lymphocytes in autoimmune diseases
- BlyS and anti-BlyS
- Fc-gamma receptors
- Immunological homunculus
- The role of MHC/peptide tetramers for tracking autoreactive T cells
- Mast cells and autoimmunity
- Anti-receptor autoantibodies
- Intrathymic expression of self-antigens
- T cell receptor antagonism
- Angiogenesis in arthritis
- Anti heat shock protein 60 immunity and atherosclerosis
- Signals for T cell activation and regulation
- Role of innate V/S acquired autoimmune responses in human cardiomyopathies
- Primary epitopes for MHC restricted autoimmune disorders
- Regulatory T cells in rheumatic diseases – from bench to bedside
- Antibody affinity maturation
- Multiple pathways of apoptosis in naïve and memory lymphocytes
- Regulation of cytokine production by PI3K
- Human NK cells: their surface receptors and function
- Atherosclerosis, angiogenesis, and autoimmunity and gamma delta T cell
- Complement and kidney disease
- Innate autoreactivity
- Neutrophil alteration in autoimmune diseases
- Molecular signaling of apoptosis in aging and autoimmunity
- Structure, function and pathogenetic significance of Ro ribonucleoproteins
- NKT cell biology; their mechanisms in disease control
- Antiendothelial cell antibodies, with special emphasis on HSP-60
- TOLERANCE
- Mechanisms of immune tolerance
- Mechanisms and promise of immune tolerance in therapy of SLE
- Tolerance deficits that are of most relevance to human autoimmunity
- Mucosal tolerance for the treatment of autoimmune diseases
- Natural autoimmunity
- Differences in tolerance mechanisms in the T and B cell compartments
- Susceptibility/resistance to autoimmunity
- Nuclear molecules as mediators of inflammation
- DIAGNOSTICS
- Peptides as autoantigens
- Novel recombinant autoantigens
- Micro-array technology for probing the immune system
- Tetramers for detection of autoreactive T cells
- New technologies in the detection of autoantibodies especially antigen arrays and
addressable laser beads
- Novel autoantigens in neurological diseases: diagnostic and pathogenic considerations
- Challenges for the clinical autoantibody laboratory
- Algorithms in autoimmunity diagnostics
- Immune informatics
- Definition of autoimmune epitopes
- Prediction and prevention of type 1 diabetes
- Antinucleophosmin antibodies in murine and human SLE
- Anti-glycan approach
- IBD/MS indications
- HORMONAL
- Autoimmunity and pregnancy
- Pregnancy and lupus/antiphospholipid syndrome
- Sex-based differences
- The role of glucocorticoid hormones in T cell differentiation and selection
- Pregnancy and connective tissue diseases
- INFECTION
- Infectious components and autoimmunity and/or mucosal immunity and autoimmunity
- Microbial B cell super antigens and their potential to cause inflammation
- Vaccination and autoimmunity
- Adjuvant and autoimmunity
- Coxsackie viruses and autoimmune epithelitis
- The role of commensal bacteria in inflammation and autoimmunity
- ANIMAL MODELS
- Animal models of vasculitis and glomerulonephritis
- New knockout mice
- DISEASES
- Atherosclerosis and autoimmunity
- Vasculitis
- Sjøgren's disease
- Monoclonal thyroid stimulating antibodies and thyroid autoimmunity
- The cellular and molecular basis of primary biliary cirrhosis
- Antiphospholipid Abs in reproductive failure/infertility
- Antiphospholipid antibody and mechanism of the thrombus formation
- Rheumatoid arthritis as a paradigm of new therapies for autoimmune disorders
- The role of the thymus in myasthenia gravis
- Autoimmune hepatitis
- Pemphigus vulgaris
- Autoimmune bullous dermatoses
- Systemic autoimmune diseases presenting with skin symptoms
- Borderline, ligand diseases between autoimmunity and different fields of dermatology
- Allergy and autoimmunity
- The associations between different autoimmune diseases
- Multiple sclerosis and regulatory cells
- Neuroimmunology
- Early microvascular changes in scleroderma
- The role of antibody and B cells in rheumatoid arthritis
- Autoimmunity associated with immune deficiency diseases
- Paraneoplastic autoimmunity
- Type 1 diabetes
- Immunology of cardiovascular disease
- The role of thrombin in autoimmune neurological disease
- Autoimmunity to HSP and ox-LDL in atherosclerosis/vasculitis
- Cognition and autoimmunity
- Therapy of ANCA-associated vasculitis
- Inflammatory clearance of apoptotic cells in vasculitis and lupus
- Immunoendocrine changes in healthy subjects and SLE patients during pregnancy
- Pulmonary hypertension in scleroderma
- Autoimmunity in the central nervous system
- Autoimmunity to endothelial cells – from scleroderma to atherosclerosis
- Cardiovascular involvement in rheumatic diseases
- B cells and primary biliary cirrhosis
- B cell clonality in Sjøgren’s Syndrome: histopathological analysis and response to
rituximab
- Snow white duodenum as an underlying disease in autoimmune
- Immune reactions against silicone implants
- THERAPY
- IVIG
- Gene therapy and autoimmune disease
- Wheat as a source of compounds against cancer and autoimmune diseases
- Peptide therapy for autoimmune disease
- Adoptive cellular gene therapy of autoimmune disease
- Immunopoiesis, transplantation and the treatment of autoimmunity
- Remodelling in systemic autoimmune diseases by differentiated stem cells or gene therapy
- Clinical and management aspects of SLE
- Therapeutic vaccines for autoimmune disease, T cell vaccination, drug- vaccines against
- myasthenia gravis, drugs-vaccines against lupus
- Statins in treatment of autoimmune disease
- Novel biologics in autoimmune disorders
- Cellcept – an advance in the treatment of lupus nephritis
- Use of monocloral therapy for the treatment of uveitis
- Leflunomide-induced lung injury
- Therapeutic strategies in systemic necrotizing vasculitis
- PROGNOSIS
- Predicting autoimmunity
- Preventive measurements in autoimmunity
- Clinical activity indexes
- CANCER
- Tumor-associated autoantibodies as indicators of cancer development
- Nutraceuticals in supportive treatment of cancer and autoimmune diseases
- Lymphoma and autoimmune rheumatic diseases
- PATIENTS SESSIONS
- Special sessions for patients will take place with lectures by experts in various fields of autoimmune diseases.
- Supported by American Autoimmune Related Diseases Association (AARDA) and Associazione Patologie Autoimmuni Internazionale (APAI).
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