|
|
|
| TUESDAY,
MAY 7, 2002 |
| POSTER SESSION 2 |
| 1 |
2-AMINOPERIMIDINE IS AN
EFFECTOR OF CHOLINESTERASES
Y. Shalitin, D. Segal, D. Gur, Israel |
| 2 |
PERIPHERAL BINDING OF ETHOPROPAZINE
TO HORSE SERUM BUTYRYLCHOLINESTERASE
E. Reiner, G. Sinko, A. Stuglin, V. Simeon-Rudolf, Croatia
|
| 3 |
SOME CONSIDERATIONS TO MOLECULAR
MECHANISM OF CHOLINESTERASE CATALYSIS
N.B. Brovtsyna, E.V. Rozengart, A.A. Suvorov, S.N. Moralev,
Russia |
| 4 |
PHOSPHONYLATION OF ACETYLCHOLINESTERASE
AND THE PROPENSITY FOR REACTIVATION ANALYZED BY CHIRALITY AND MUTAGENESIS
Z. Kovarik, Z. Radic, H.A. Berman, P. Taylor, Croatia, USA
|
| 5 |
THE
FIRST TWO NATURALLY OCCURRING ACTIVATORS / REACTIVATORS OF ACETYLCHOLINESTERASE
R. Gupta, S.S. Thakur, India |
| 6 |
KINETICS OF INTERACTION
OF ETHOPROPAZINE ENANTIOMERS WITH BUTYRYLCHOLINESTERASE AND ACETYLCHOLINESTERASE
G. Sinko, Z. Radic', V. Simeon-Rudolf, E. Reiner, P. Taylor,
Croatia, USA |
| 7 |
REACTIVATION STUDY INDICATES
THAT THE ORIENTATIONS OF HI-6 MAY DIFFER IN REACTIVATING ACETYLCHOLINETERASE
INHIBITED WITH ORGANOPHOSPHATE AND ORGANOPHOSPHONATES
C. Luo, A. Saxena, H. Leader, Z. Radic, D.M. Maxwell, P.
Taylor, B.P. Doctor, USA |
| 8 |
KINETIC AND X-RAY CRYSTALLOGRAPY
STUDIES ON THE INTERACTION OF CHOLINESTERASES WITH THE ANTI-ALZHEIMER
DRUG RIVASTIGMINE
P. Bar-On, M. Harel, C.B. Millard, A. Enz, J.L. Sussman,
I. Silman, Israel, USA, Switzerland |
| 9 |
ATTEMPTS TO ENGINEER AN
ENZYME-MIMIC OF BUTYRYLCHOLINESTERASASE BY SUBSTITUTION OF THE SIX
DIVERGENT AROMATIC AMINO ACIDS IN THE ACTIVE CENTER OF ACETYLCHOLINESTERASE
D. Kaplan, A. Ordentlich, D. Barak, N. Ariel, C. Kronman,
B. Velan,
A. Shafferman, Israel, |
| 10 |
MALDI-TOF/MS ANALYSIS OF
ACETYLCHOLINESTERASE-LIGAND CONJUGATES: A TOOL FOR RESOLUTION OF
MECHANISTIC PATHWAYS
E. Elhanani, A. Ordentlich, O. Dgany, D. Kaplan, Y. Segall,
R. Barak, B. Velan, A. Shafferman, Israel |
| 11 |
INFLUENCE OF WATER ON THE
FUNCTION OF ACETYLCHOLINESTERASE
R.H. Henchman, K. Tai, T. Shen, J.A. McCammon, USA |
| 12 |
THE FLUCTUATING SYNAPSE
K. Kaufmann, Germany |
| 13 |
X-RAY
STRUCTURE OF TORPEDO AChE COMPLEXED WITH BIFUNCTIONAL LIGANDS RELATED
TO HUPA: NOVEL DRUGS FOR TREATMENT OF ALZHEIMER'S DISEASE
D.W. Wong, H.M. Greenblatt, D. Shaya, P.R. Carlier, Y.-P.
Pang, Y.-F. Han,
I. Silman, J.L. Sussman, Israel, USA, Hong Kong
|
| 14 |
CRYSTALLIZATION AND DETERMINATION
OF THE X-RAY STRUCTURE OF HUMAN ACHE
H. Dvir, G. Kryger, J.L. Johnson, T.L Rosenberry, I. Silman,
J.L. Sussman, Israel, USA |
| 15 |
3D STRUCTURE OF TORPEDO
CALIFORNICA ACETYLCHOLINESTERASE COMPLEXED WITH HUPRINE X
H. Dvir, D.M. Wong, M. Harel, X. Barril, M. Orozco, F.J.
Luque, P. Camps,
T.L. Rosenberry, I. Silman, J.L. Sussman, Israel,
Spain, USA |
| 16 |
LIGAND INDUCED CONFORMATIONAL
CHANGES IN THE OMEGA LOOP OF ACETYLCHOLINESTERASE REVEALED BY FLUORESCENCE
SPECTROSCOPY
J. Shi, Z. Radic, A. Boyd, P. Taylor, USA |
| 17 |
bis-ACTING
GALANTHAMINE DERIVATIVES AS IMPROVED DRUGS IN THE SYMPTOMATIC TREATMENT
OF ALZHEIMER'S DISEASE
H.M. Greenblatt, C. Guillou, B. Badet, C. Thal, I. Silman,
J.L. Sussman, Israel, France |
| 18 |
COMPARISON OF TWO REACTION
SCHEMES FOR THE HYDROLYSIS OF ACETYLTHIOCHOLINE BY BUTYRYLCHOLINESTERASE
V. Simeon-Rudolf, G. Sinko, A. Stuglin, J. Stojan, M. Golicnik,
E. Reiner, Croatia, Slovenia |
| 19 |
QUANTAL ACETYLCHOLINE RELEASE
THROUGH MEDIATOPHORE PROTEOLIPID OVER-EXPRESSED IN NEUROBLASTIC
CELLS
A. Bloc, J. Falk-Vairant, M. Malo, M. Israel, Y. Dunant,
Switzerland, France |
| 20 |
STIMULATION
OF NICOTINIC RECEPTORS INDIRECTLY INCREASES ACETYLCHOLINE RELEASE
IN RAT STRIATUM
V. Dolezal, V. Zemlickova, S. Tucek, Czech Republic |
| 21 |
CAPILLARY
ZONE ELECTROPHORESIS DETECTS NWANTED CHOLINESTERASE-BOUND HIDDEN
LIGANDS THAT MODULATE ENZYME CONFORMATIONAL STABILITY
D. Rochu, F. Renault, C. Bon, P. Masson, France |
| 22 |
CRYSTAL STRUCTURE OF TORPEDO
CALIFORNICA ACETYLCHOLINESTERASE WITH A NOVEL GALANTHAMINE DERIVATIVE:
IMPLICATIONS FOR THE DESIGN OF NEW ANTI-ALZHEIMER DRUGS
M.C. Siotto, C. Bartolucci, D. Lamba, Italy |
| 23 |
X-RAY STRUCTURE OF SOMAN-AGED
HUMAN BUTYRYLCHOLINESTERASE
F. Nachon, Y. Nicolet, P. Masson, J-C. Fontecilla-Camps,
O. Lockridge, France, USA |
| 24 |
STUDIES ON DYNAMICAL TRANSITIONS
IN CHOLINESTERASES
F. Gabel, M. Weik, L. Brochier, D. Fournier, P. Masson, B.
P. Doctor, I. Silman, G. Zaccai, France, USA, Israel |
| 25 |
TETANIC FADE IS REVEALED
BY BLOCKING PRESYNAPTIC NICOTINIC RECEPTORS CONTAINING ALFA4BETA2
AND ALFA3BETA2 SUBUNITS AFTER REDUCING THE SAFETY FACTOR OF NEUROMUSCULAR
TRANSMISSION
M. Faria, L. Oliveira, M.A. Timoteo, M.G.B. Lobo, P. Correia-de-Sa,
Portugal |
| 26 |
MOLECULAR CHARACTERISATION
OF ACETYLCHOLINESTERASE FROM THE PEACH-POTATO APHID MYZUS PERSICAE(SULZ.)
M.C. Andrews, C.G. Bass, M.S. Williamson, G.D. Moores, UK
|
| 27 |
PECULIARITIES OF KINETIC
BEHAVIOUR OF FISH`S/ABRAMIS BALLERUS/ BLOOD SERUM CHOLINESTERASE
V.D. Tonkopii, Russia |
| 28 |
STRUCTURAL INSIGHTS INTO
THE INTERACTIONS AT THE ACETYLCHOLINESTERASE PERIPHERAL ANIONIC
SITE
Y. Bourne, P. Taylor, H.A. Berman, Z. Radic, P. Marchot,
France, USA |
| 29 |
LETHAL EFFECTS OF HEAD-TO-TAIL
3-ALKYLPIRIDINIUM POLYMERS ISOLATED FROM THE MARINE SPONGE RANIERA
SARAI: ACHE INHIBITION OR UNSPECIFIC BINDING TO SERUM PROTEINS?
M. Bunc, K. Sepcic, A. Rotter, T. Turk, A. Vidmar, D. Suput,
Slovenia |
| 30 |
PIPERONYL
BUTOXIDE: A SPECIFIC INHIBITOR OF INSECTICIDE RESISTANT ACETYLCHOLINESTERASE
R.V. Gunning, Australia |
| 31 |
SIGNIFICANCE OF PARAMETERS
BETWEEN VARIOUS KINETIC SCHEMES FOR CHOLINESTERASES
J. Stojan, M. Golicnik, Slovenia |
| 32 |
STUDIES OF ACETYLCHOLINESTERASE
FROM THE PEACH-POTATO APHID, MYZUS PERSICAE(SULZ.)
N. Javed, M.S. Williamson, A.L. Devonshire, R.C. Viner, T. Lewis,
G.D. Moores, UK |
| 33 |
EXPLORING
THE ACHE GORGE WITH GALANTHAMINE
G. Fels, E. Linnemann, E. Luttmann, C. Pilger, Germany |
| 34 |
HYSTERESIS IN BUTYRYLCHOLINESTERASE
CATALYSIS: EVIDENCE FOR SUBSTRATE-INDUCED CONVERSION OF THE ENZYME
FROM LATENT TO OPERATIVE FORM
P-Y. Masson, M-T. Froment, F. Nachon, L.M. Schopfer, France,
USA |
| 35 |
A CALCIUM-PROTON ANTIPORT
IN CHOLINERGIC AND GLUTAMATERGIC SYNAPTIC VESICLES
M. Cordeiro, V. Bancila, A. Bloc, Y. Dunant, Switzerland |
| 36 |
OXACHEIN,
A NOVEL POTENT INHIBITOR OF ACETYLCHOLINESTERASE FROM A PLANT--
OXALIS CORNICULATA L.
R. Gupta, A. Gupta, India |
| 37 |
MECHANISM OF ACETYLCHOLINESTERASE
INHIBITION BY FASCICULIN: A 5 NANOSECOND MOLECULAR DYNAMICS SIMULATION
K. Tai, T. Shen, R.H. Henchman, Y. Bourne, P. Marchot, J.A.
McCammon, USA, France |
| 38 |
PROF. RENE COUTEAUX AND
HIS PRESYNAPTIC 'ACTIVE ZONE'
S. Tsuji, France |
|
