SCIENTIFIC PROGRAM

WEDNESDAY, OCTOBER 6, 1999

SESSION IX
ENDOTHELIAL DYSFUNCTION: PATHOGENESIS AND TREATMENT

Co-Chairperson: C. Thuillez, France

A. Haj-Yehia, Israel

09:00 CLINICAL INVESTIGATION OF ENDOTHELIAL DYSFUNCTION IN DIABETIC AND HYPERTENSIVE PATIENTS
C. Thuillez, France

09:30 EFFECTS OF CARDIOVASCULAR RISK FACTORS ON VASCULAR SUPEROXIDE AND NITRIC OXIDE PRODUCTION
T. Munzel, Germany

10:00 RECENT DEVELOPMENTS IN THE PATHOGENESIS AND TREATMENT OF ENDOTHELIAL DYSFUNCTION
E. Anggard, UK

10:30 COFFEE BREAK

11:00 NITRIC OXIDE DONORS: THE ZERO TOLERANCE ALTERNATIVE ADDRESSING ENDOTHELIAL DYSFUNCTION AND OTHER OXIDATIVE STESS-MEDIATED PATHOLOGIES
L.Z. Benet, E.E. Anggard, A. Haj-Yehia, USA

11:30 LOCAL DELIVERY OF PDGF RECEPTOR-SPECIFIC TYRPHOSTIN INHIBITS NEOINTIMAL FORMATION IN RAT
I. Fishbein, S. Banai, J. Waltenberger, L. Rabinovich, M. Chorny, A. Levitzki, A. Gazit, D.S. Gertz, G. Golomb, Israel

09:00 - 11:30 HALL B

SESSION X
RATIONAL APPROACHES TO COMBAT RESISTANCE TO ANTI-INFECTIVE DRUGS

Co-Chairperson: E. Bergone-Berezin, France

R. Kitzes-Cohen, Israel

09:00 RESISTANCE TO ANTI-INFECTIVE DRUGS - A GLOBAL PROBLEM
R. Kitzes-Cohen, Israel

09:30 CORRELATION BETWEEN ANTIBIOTIC PHARMACOKINETCS AND BACTERIAL RESISTANCE
E. Bergogne-Berezin, France

10:00 ANTIBIOTIC PRESCRIBING AND RESISTANCE
I. Francetic, S. Kaleniae, Croatia

10:30 COFFEE BREAK

11:00 NEW APPROACHES TO OVERCOMING ANTIMICROBIAL RESISTANCE
B. Rouviex, France

11:30 - 12:30

POSTER VIEWING AND DISCUSSION
A. ENDOTHELIAL DYSFUNCTION: PATHOGENESIS AND TREATMENT

Chairperson: A. Golik, Israel

SEROLOGICAL ICAM AND ELAM IN PREDNISON AND DAPSONE TREATMENT OF ALLERGIC VASCULARITIS
M. Alecu, G. Coman, O. Coman, S. Alecu, L. Coman, L. Galatescu, Romania

INACTIVATION OF THE ENDOTHELIM AGONIST AND ANTAGONIST PEPTIDES BY THE RAT KIDNEY METALLOENDOPEPTIDASE
J. Janas, D. Sitkiewicz, R.M. Janas, Poland

THE EFFECTS OF TREATMENT BY ISOSORBIDE-5-MONONITRATE TO FUNCTIONAL ACTIVITY OF HUANILATE CYCLASE IN PATIENTS WITH CHRONIC HEART FAILURE
L.I. Olbinskaya, A.V. Ushakova, J.M. Syzova, Russia

DOES PHLOGENZYM IMPROVE MICROCIRCULATION?
E. Pule, M. Skromanis, A. Skutelis, I. Purvins, V. Mikazhans, J. Ansbergs, M. Zeibarts, Latvia

CARDIO AND ANGIOPROTECTIVE ACTIVITY OF HIPOLIPIDEMIC DRUGS
I. Purvins, E. Pule, V. Mikashans, M. Skromanis, A. Skutelis, S. Purvina, Latvia

11:30 - 12:30

POSTER VIEWING AND DISCUSSION
B. RATIONAL APPROACHES TO COMBAT RESISTANCE TO ANTI-INFECTIVE DRUGS

DESTRUCTIVE PNEUMONIA TREATMENT
L.A. Aleksanyan, A.L. Vyortkin, E.V. Krivtsova, E.A. Prohorovich, A.S. Makaryan, Russia

SUSCEPTIBILITY TESTING IN GENERAL PRACTICE IS INSUFFICIENT
L. Bjerrum, P. Grinsted, P. Hyltoft Petersen, P. Sogaard, Denmark

USING OF "INTERFERON" IN CHILDREN WITH INTRACELLULAR INFECTION (ICI) LIVING IN CLOSED CHILD INSTITUTION (CCI)
Z.I. Ismagilova, E.I. Etkina, E.V. Bobkova, A.R. Mavzutov, Russia

A STUDY TO DETERMINE THE PENETRATION OF CLINAFLOXACIN (CI-960) INTO BILE AFTER A SINGLE ORAL DOSE IN PATIENTS UNDER GOING ELECTIVE CHOLECYSTECTOMY
J.M. Tellado, J. Galduf, C. Fiuza, Spain, N. Bron, N.J. Hounslow, UK, G. Hernandez, J. Chaves, J. Cebrecos, Spain, E. Randinitis, USA

ANTIBACTERIAL DRUG USE AND ANTI-MICROBIAL RESISTANCE IN UNIVERSITY HOSPITALS IN VILNIUS AND STOCKHOLM IN 1997
J. Gulbinovic, Lithuania, K.-E. Mybrack, Sweden, J. Bytautiene, Lithuania, B. Wettermark, U. Bergman, Sweden

EVALUATION OF CIPROFLOXACIN PRESCRIBING IN A TERTIARY HOSPITAL
D. Michael, Z. Stoler, R. Kitzes-Cohen, Israel

TICLOPIDINE - ADVERSE REACTIONS
R. Kitzes-Cohen, M. Schneider, A. Wasserman, A. Hanoch, D. Koos, Israel

SENSITIVITY AND RESISTANCE OF E. COLI IN URINOCULTURES IN CROATIA IN 1998
A. Krajac Cupic, K. Makar Ausperger, M. Bilusic, V. Macolic Sarinic, I. Francetic, B Vrhovac, Z. Perisic, V. Kruzicevic, Croatia

A RANDOMIZED DOUBLE-BLIND COMPARATIVE STUDY OF TWO TOPICAL FORMULATIONS OF ANTIMYCOTIC, ANTIBACTERIAL AND CORTICOSTEROIDAL AGENTS
E. Tur, Israel

11:30 - 12:30

POSTER VIEWING AND DISCUSSION
C. TREATMENT OF HYPERTENSION AND OTHER CARDIOVASCULAR DISEASES

HEMODYNAMIC AND HEMORHEOLOGIC EFFECTS OF FOSINOPRIL, VALSARTAN AND IRBESARTAN ON PATIENTS WITH OBLITERATIVE ARTERIOPATHIES OF THE LOWER LIMBS
A. Brassai, Gy. Feszt, Z. Brassai, K. Mako, L. Domjanschitz, Romania

TREATMENT OF FAMILIAL ARTERIAL HYPERTENSION (FAH) : PLASMAFILTRATION AND INHIBITORS ACE
Yu. Bubnov, I.V. Miliagina, V.A. Miliagin, B. Namakanov, Russia

L-NMMA (A NITRIC OXIDE SYNTHASE INHIBITOR) IS EFFECTIVE IN THE TREATMENT OF CARDIOGENIC SHOCK
G. Cotter, E. Kaluski, A. Blatt, R. Zaidenstein, O. Milovanov, M. Metzger, Z. Vered, A. Golik, Israel

11:30 - 12:30

POSTER VIEWING AND DISCUSSION
C. TREATMENT OF HYPERTENSION AND OTHER CARDIOVASCULAR DISEASES (cont)

RELATIONSHIP BETWEEN PLASMA CONCENTRATIONS OF CALCIUM CHANNEL BLOCKERS AND BLOOD PRESSURE DECREASE IN HEALTHY VOLUNTEERS
K. Davoic-Svajcer, A. Sabo, V. Jakovljevic, M. Mikov, M. Stanulovic, I. Samojlik, A. Raskovic, B. Banic, Yugoslavia

AN INFLUENCE OF  A  THERAPY OF MILD/MODERATE ARTERIAL HYPERTENSION WITH CONTROLLED RELEASE PREPARATIONS OF NIFEDIPINE, KARVEDILOL, AND RAMIPRILE ON THE LIPID PROFILE
S.A. Kudriavtseva, V.V. Dmitriev, K.V. Litovchenko, S.N. Nakonechnikov, K.Yu. Petrosian, M.A. Gurtueva, V.Yu. Savel'ev, Russia

A THERAPY OF MILD AND MODERATE HYPERTENSION WITH KARVEDILOL
S.A. Kudriavtseva, V.V. Dmitriev, S.N. Nakonechnikov, V.Y. Savel'ev, Russia

ANGIOTENSIN-CONVERTING-ENZYME (ACE) INHIBITOR INTAKE ASSOCIATED WITH DIMINISHED BLADDER CANCER RISK
K. Farker, J. Husing, E. Greiser, A. Hoffman, MURC Study Group, Germany

COMPERATIVE EFFECTS OF THE THERAPUTIC COMBINATIONS WITH ISOSRBIDE DINITRATE (ID) AND UNFRACTIONATED HEPARIN (UFH) VS LOW MOLECULAR WEIGHT HEPARIN (LMWH) AND HEPARIN MONOTHERAPY IN ACUTE CORONARY SYNDROME (ACS) OF THE ELDERLY
L.B. Lasebnik, A.V. Gavrilova, Russia

THERAPEUTICAL EFFICACY AND SAFETY OF ENALAPRIL MALEATE (VASOPREN) IN PATIENTS WITH ESSENTIAL HYPERTENSION
I. Ivanov, D. Dobreva, O. Vassileva, V. Stojanovski, S. Ninkova, A. Hubenova, At. Kissiov, L. Grouev, Chr. Kojouharov, Bulgaria

EVALUATION OF THE ANTIRRHYTMIC DRUG THERAPY IN AMBULATORY PATIENTS
L. Keric, R. Skbic, S. Stoisavljevic-Satara, M. Stanulovic, Bosnia

EFFECT OF DIFFERENT ANTIHYPERTENSIVE TREATMENTS ON THE PROGRESSION OF MICROALBUMINURIA IN DIABETIC PATIENTS
S. Ljubic, I. Pavlic-Renar, Z. Metelko, Croatia

CHRONOTHERAPEUTIC APPROACH TO THE MANAGEMENT OF ANTIHYPERTENSIVE TREATMENT WITH LISINOPRIL
C. Macchiarulo, R. Pieri, M. Montagnani, D. Chieppa-Mitolo, A. Pirrelli, Italy

24-AMBULATORY BLOOD PRESSURE MONITORING AND LIFE QUALITY AT OLD PATIENTS WITH ISOLATED SYSTOLIC HYPERTENSION: NITRENDIPIN VERSUS ENALAPRIL-NITRENDIPIN
I.V. Marchenco, S.V. Nedogoda, Russia

PHARMOCODYNAMIC OF MIDODRINE AT PATIENTS WITH ESSENTIAL ORTHOSTATIC HYPOTENSION
E.G. Mazhbits, S.V. Nedogoda, Russia

b-BLOCKADE THERAPY IMPROVES AUTONOMIC NERVOUS SYSTEM DYSFUNCTION IN CHRONIC HEART FAILURE
S.V. Nedogoda, Russia

NIFEDIPINE RETARD AND FELODIPINE ER IN THE TREATMENT OF ELDERLY HYPERTENSIVES COMPARISION BY AMBULATORY BLOOD PRESSURE MONITORING
L.I. Olbinskaya, B.A. Khapaev, E.A. Nikitina, Russia

8-WEEK MOEXIPRIL TREATMENT IMPROVES LEFT VENTRICULAR DYSFUNCTION DUE TO MILD-MODERATE ARTERIAL HYPERTENSION AT POSTMENOPAUSAL WOMEN
V.I. Petrov, S.V. Nedogoda, V.A. Zhelezkin, Russia

11:30 - 12:30

POSTER VIEWING AND DISCUSSION
C. TREATMENT OF HYPERTENSION AND OTHER CARDIOVASCULAR DISEASES (cont)

 

THE RESULTS OF LOZARTAN EFFECT ON DIAMETER, TENSION AND DOPPLEROGRAPHIC BLOODFLOW INDEXES IN COMMON CAROTIC ARTERIES
IN PATIENTS WITH ESSENTIAL HYPERTENSION
V. Pyrochkin, E. Shantilo, E. Mironchik, Belarus

ADEQUACY OF CEFACLOR DOSING IN TREATMENT OF SYSTEMIC INFECTIONS
A. Sabo, M. Mikov, Z. Tomic, V. Jakovljevic, K. Djakovic, M. Stanulovic, Yugoslavia

THE EXAMINATION OF WATER-SOLUBLE VITAMINS CONCENTRATION IN PATIENTS WITH CHRONIC CARDIOVASCULAR AND RESPIRATORY DISEASES
E. Shish, O. Demidova, N. Litvak, R. Belitskaya, L. Krasnyh, Russia

AN INTERETHNIC STUDY OF ANGIOTENSIN CONVERTING ENZYME INHIBITION ON HEART RATE VARIABILITY
M. Van Wyk, De.K. Sommers, J.R. Snyman, A. Kotze, South Africa

COMPARISON OF ANTIARRHYTHMIC EFFECTS OF HAWTHORN (CRATAEGUS) EXTRACT AND
SOME PLANT EXTRACTS
V. Vdovichenko, V. Fiodorov, V. Kozlovsky, T. Korshak, Belarus

THE INFLUENCE OF THE PROLONGED INHIBITORS AEE ON THE LEFT VENTRICLE DIASTOLIC FUNCTION IN ARTERIAL HYPOTENSION CASES
A.L. Vyortkin, S.V. Zits, Russia

12:30 - 13:15 HALL A

PLENARY LECTURE

12:30 SHOULD WE HAVE DRUGS FOR PLEASURE
M. Reidenberg, USA

13:15 LUNCH BREAK

14:30 - 16:30 HALL A

EACPT SYMPOSIUM:
PROGRESS IN CLINICAL PHARMACOLOGY IN EASTERN EUROPE

Chairperson: M.L. Orme, UK

14:30 CLINICAL PHARMACOLOGY IN RUSSIA
V. Kukes, Russia

14:50 CLINICAL PHARMACOLOGY IN ESTONIA
L. Rago, Estonia

15:10 CLINICAL PHARMACOLOGY IN THE CZECH REPUBLIC
T. Sechser, Czech Republic

15:30 CLINICAL PHARMACOLOGY IN BULGARIA
V. Vlahov, Bulgaria

15:50 GENERAL DISCUSSION

16:15 COFFEE BREAK

17:00 -

EACPT COUNCIL MEETING

COUNCIL MEETING