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2. The Insulinomimetic
Effects of Metal Ions: Potential Therapy for Diabetes Mellitus September
14-15, 2000

| Thursday,
September 14, 2000 |
| Session
I: The molecular mechanisms of action of ion metals |
| 15:00-15:15 |
Introduction: General
presentation on ion-metals as antidiabetic agents
J.H. McNeill, Canada |
| 15:15-15:45
|
Peroxovanadium compounds: Potent
phosphatase inhibitors with insulin-like effects
B.I. Posner, Canada |
| 15:45-16:15 |
PI-3 kinase and the
insulin-like effect of vanadate
J.M. Carrascosa, Spain |
| 16:15-16:45
|
Coffee Break and Poster Session |
| 16:45-17:15 |
The role of PKB in insulinomimesis
by vanadium compounds.
A.K. Srivastava, Canada |
| Friday,
September 15, 2000 |
| Session
II: The
insulinomimetic and antidiabetic effects of metal ions |
| 09:00-09:30
|
The effect of vanadium on GLUT4
translocation in skeletal muscle
I.G.Fantus, Canada |
| 09:30-10:00 |
The effect of selenium on
glucose tolerance in STZ-diabetic rats
J.H. McNeill, Canada |
| 10.00-10:30 |
The effect of vanadium on
insulin secretion in diabetic rats
G.H. Cros, France |
| 10:30-11:00 |
Coffee Break and Poster Session |
| 11:00-11:30
|
The pharmacokinetic of vanadyl
sulfate and its effect in the treatment of type 2 human diabetes
J.L.Chiasson, Canada |
| 11:30-12:15
|
Poster discussion |
| 12:15-14:00 |
Lunch Break and poster
session |
| Session
III: The antidiabetic effect of tungstate |
| 14:00-14:30
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The effects of tungstate on beta
cells
R. Gomis, Spain |
| 14:30-15:00
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Effects of tungstate on insulin
secretion in the perfused rat pancreas
J. Marco, Spain |
| 15:00-15:30 |
Regulation of islet cell
neogenesis by tungstate
J.J. Gagliardino, Argentina |
| 15:30-16:00 |
Coffee Break and Poster
Session |
| 16:00-16:30 |
The effects of tungstate on
liver and muscle
J.J. Guinovart, Spain |
| 16:30-17:00
|
Comparative cell toxicity between
vanadate and tungstate derivatives
J. Domingo, Spain |
| 17:00
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Conclusion Remarks
R.Gomis, Spain |

Hotel Calipolis, Passeig Maritim s/n, Sitges, Barcelona, Spain

Jean-Louis Chiasson, Canada

Bayer, Spain
FOR
GENERAL, REGISTRATION AND ABSTRACT ENQUIRIES
Ramon Gomis
Hospital Cl?nic i Universitari
Servei Endocrinologia i Diabetis
Villarroel, 170
08036 Barcelona, SPAIN
Tel: +34 93 2275411
Fax: +34 93 4516638
E-mail: gomis@clinic.ub.es
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