Poster Presentations

Apr 23, 2009

VIRAL HEPATITIS - f) HEPATITIS C – CLINICAL (EXCEPT THERAPY):

INTERACTION BETWEEN HEPATITIS B AND C IN HIV INFECTED PATIENTS; RISK OF DYING AMONG PATIENTS WITH A TRIPLE INFECTION
C. Smit¹, J. Arends², F. de Wolf^1,3, I.M. Hoepelman^2
1HIV Monitoring Foundation, Amsterdam, ²Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands, ³Imperial College London, London, UK

HCV INFECTED PATIENTS ARE “SPARED” FROM THE METABOLIC SYNDROME BUT NOT FROM INSULIN RESISTANCE
S. Ballestri¹, E. Violi¹, A. Lonardo¹, L.E. Adinolfi², L. Carulli¹, S. Lombardini¹, F. Scaglioni¹, M. Ricchi¹, G. Ruggiero², P. Loria^1
1Department of Internal Medicine, Endocrinology and Geriatrics, University of Modena and Reggio Emilia, Modena, ²Division of Internal Medicine and Hepatology, Second University of Naples, Naples, Italy

TRENDS IN EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS OF HCV-INFECTED PATIENTS OVER SIX YEARS: A FRENCH EXPERIENCE
C. Brouard¹, C. Pioche¹, J.P. Bronowicki², P. Couzigou³, O. Goria⁴, D. Guyader⁵, P. Hillon⁶, P. Marcellin⁷, J.P. Miguet⁸, F. Roudot-Thoraval⁹, C. Silvain¹⁰, J.P. Zarski¹¹, E. Delarocque-Astagneau^1
1Institut de Veille Sanitaire, Saint-Maurice, ²University Hospital, Nancy, ³University Hospital, Bordeaux, ⁴University Hospital, Rouen, ⁵University Hospital, Rennes, ⁶University Hospital, Dijon, ⁷University Hospital, Clichy, ⁸University Hospital, Besançon, ⁹University Hospital, Créteil, ¹⁰University Hospital, Poitiers, ¹¹University Hospital, Grenoble, France

FIBROSPLEEN: MEASURING SPLEEN STIFFNESS BY TRANSIENT ELASTOGRAPHY INCREASES ACCURACY OF STAGING OF LIVER FIBROSIS AND OF PORTAL HYPERTENSION IN CHRONIC VIRAL HEPATITIS
V. Di Marco¹, F. Bronte¹, V. Calvaruso¹, C. Cammà¹, D. Cabibi², G. Licata¹, F. Simone¹, A. Craxì^1
1Gastroenterology and Hepatology Unit, ²Histopathology, University of Palermo, Palermo, Italy

LIVER STIFFNESS IS ASSOCIATED WITH CLINICAL OUTCOME OF HCV RELATED CIRRHOSIS
A.-C. Cardoso¹, C. Stern², R. Moucari³, C. Figueiredo-Mendes², N. Giuily⁴, P. Marcellin^2
1Hepatology Service, ²Hepatology Service and INSERM U773-CRB3, Hopital Beaujon, Clichy, France, ³Hepatology Service and INSERM U773-CRB3, ⁴Hepatology Service and INSERM U773-CRB3, Hopital Beaujon, Clichy, Indonesia

TRACKING INTRAFAMILIAL SPREAD OF SEROLOGICALLY SILENT OCCULT HCV INFECTION THROUGH HUMORAL AND CELLULAR HCV-SPECIFIC RESPONSES
J.A. Quiroga¹, S. Llorente¹, I. Castillo¹, J. Bartolome¹, G. Barril^1,2, V. Carreño^1
1Fundacion para el Estudio de las Hepatitis Virales, ²Nephology, H.U. de la Princesa, Madrid, Spain

FULL-LENGTH SEQUENCE ANALYSIS OF A NEW SUBTYPE OF HEPATITIS C VIRUS GENOTYPE 1 STARTING ITS SPREAD IN A HEMODIALYSIS UNIT
S. Chevaliez¹, R. Brillet², J. Sehounou³, J. Fix², J.-M. Pawlotsky^2
1French National Reference Center for Viral Hepatitis B, C and Delta, INSERM U841, Hôpital Henri Mondor, ²University Paris 12, Creteil, France, ³Gastroenterology, Hôpital Hubert Kutuku Maga, Cotonou, Benin

NON-INVASIVE ASSESSMENT OF HEPATIC LIPID COMPOSITION: LIPID POLYUNSATURATION DECREASES WITH INCREASING FIBROSIS IN CHRONIC HEPATITIS C
J.F.L. Cobbold¹, J.H. Patel¹, R.D. Goldin², M.E. Crossey¹, J. Fitzpatrick¹, S.D. Taylor-Robinson¹, I.J. Cox^3
1Department of Hepatology and Gastroenterology, ²Department of Histopathology, ³Imaging Sciences Department, Imperial College London, London, UK

EPIDEMIOLOGY OF HCV AND HBV IN THE GENERAL POPULATION: A SURVEY IN A SOUTHERN ITALIAN TOWN
R. Cozzolongo¹, A.R. Osella², S. Elba¹, J. Petruzzi³, G. Buongiorno³, V. Giannuzzi¹, G. Leone¹, C. Bonfiglio², E. Lanzilotta¹, O.G. Manghisi¹, G. Leandro^1
1Gastroenterology, ²Epidemiology and Biostatistics, ³Gastroenterology, S de Bellis Hospital IRCCS, Castellana Grotte, Italy

INDIVIDUAL PATIENT DATA META-ANALYSIS OF TRANSIENT ELASTOGRAPHY DIAGNOSTIC ACCURACY IN LIVER FIBROSIS ASSESSMENT OF CHRONIC HEPATITIS C PATIENTS (TE IPD STUDY)
E. Pambrun¹, V. Bouteloup¹, V. de Lédinghen^2,3, J. Asselineau^4,5, M. Fraquelli⁶, M. Brunetto⁷, X. Forns⁸, H. Saito⁹, P. Nahon¹⁰, M. Pirisi¹¹, R. Thiébaut¹, P. Perez^4,5
1Centre de Recherche Inserm U897, ISPED, Université Bordeaux 2, Bordeaux, ²Centre d'Évaluation de la Fibrose, Hôpital Haut-Lévêque, CHU Bordeaux (University Hospital), Pessac, ³Inserm U889, Université Bordeaux 2, ⁴Clinical Epidemiology Unit (USMR), CHU Bordeaux (University Hospital), ⁵Inserm CIC-EC 7, ISPED, Université Bordeaux 2, Bordeaux, France, ⁶II Division Gastroenterology, IRCCS Fondazione Ospedale Policlinico, Mangiagalli e Regina Elena, Milano, ⁷UO Gastroenterologia ed Epatologia Ospedaliera, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, ⁸Liver Unit, Institut de Malaties Digestives, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain, ⁹Department of Internal Medicine, School of Medicine, KEIO University, Tokyo, Japan, ¹⁰Service d'Hepato-Gastro-Enterologie, Hopital Jean Verdier AP-HP, Bondy, France, ¹¹Department of Clinical and Experimental Medicine (DiMeCS), University of Eastern Piedmont “A. Avogadro”, Novara, Italy

HUMORAL NEUTRALIZING RESPONSE TO HCV DURING HIV COINFECTION AND LIVER TRANSPLANTATION
G. Maurin¹, A.-M. Roque-Afonso², P. Vaghefu³, M. Gigou³, J.-C. Duclos-Vallée³, F.-L. Cosset⁴, D. Samuel³, D. Lavillette⁴, C. Féray^5
1Ecole Normale Supérieure, INSERM 758, Lyon, ²Centre Hépato-Biliaire, ³INSERM 785, Villejuif, ⁴INSERM 758, Lyon, ⁵INSERM 948 University Nantes, Nantes, France

STEATOSIS INDUCES ANGIOGENESIS IN CHRONIC HEPATITIS C
M. Kukla¹, A. Gabriel², M. Wilk³, L. Liszka³, M. Petelenz⁴, I. Frelich^2
1Physiology, ²Pathomorphology, Medical University of Silesia in Katowice, Zabrze, ³Histopathology, Medical University of Silesia in Katowice, Katowice, ⁴Department of Basic Biomedical Science, Medical University of Silesia in Katowice, Sosnowiec, Poland

DOES ACUTE HEAPTITIS C INFECTION AFFECT THE CENTRAL NERVOUS SYSTEM IN HIV INFECTED INDIVIDUALS?
L. Garvey¹, A. Winston¹, E. Scotney¹, D. Yerrakalva¹, J. Allsop², E. Thomson¹, V. Grover¹, J. Main¹, J. Cox², M. Wylezinska², S. Taylor-Robinson^1,2
1Division of Medicine, ²Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College, London, UK

FATIGUE IN CHRONIC HEPATITIS C INFECTION IS RELATED TO IMMUNE ACTIVATION AND ABNORMALITIES IN TRYPTOPHAN METABOLISM
M. Gess^1,2, T. Lee³, N. Tatman¹, T. Rahman¹, S. Clark¹, M. Cowan², J. Sheldon⁴, D. Holt³, D. Forton^1
1Department of Gastroenterology and Hepatology, St George`s Hospital, <sup>2</sup>Cellular and Molecular Medicine, <sup>3</sup>Analytical Unit, <sup>4</sup>Basic Medical Sciences, St George`s University of London, London, UK

IMPACT OF HEPATITIS C VIRUS INFECTION ON LIVER-RELATED MORTALITY IN A LARGE COMMUNITY-BASED COHORT OF INNER CITY RESIDENTS
J. Grebely¹, J. Raffa², C. Lai³, M. Krajden⁴, B. Fischer⁵, T. Kerr³, G. Dore¹, M. Tyndall^3
1National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia, ²Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, ³British Columbia Centre for Excellence in HIV/AIDS, ⁴British Columbia Centre for Disease Control, ⁵Simon Fraser University, Vancouver, BC, Canada

RACIAL DIFFERENCES IN GLOBULIN LEVELS IN PATIENTS WITH HEPATITIS C AND VIROLOGIC RESPONSE TO PEGYLATED INTERFERON AND RIBAVIRIN
N. Reau, R. Satoskar, A. DeVoss, G. Reddy, H. Te, S. Mohanty, L. Espinosa, D. Jensen
Center for Liver Diseases, University of Chicago, Chicago, IL, USA

SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF GS-9450 IN HEALTHY MALE AND FEMALE VOLUNTEERS
F. Höppener¹, J.A. Kim², M.J. Park², H.J. Choi^3
1KENDLE Clinical Pharmacology Unit, Utrecht, The Netherlands, ²R & D Park, LG Life Sciences, Ltd., Daejeon, ³Regulatory Affairs & Product Development, LG Life Sciences, Ltd., Seoul, South Korea

SERUM LEVELS OF CHEMERIN, VASPIN, VISFATIN AND SPECAM-1 IN PATIENTS WITH CHRONIC HEPATITIS C
M. Kukla¹, K. Żwirska-Korczala¹, A. Gabriel², M. Waluga³, W. Mazur⁴, A. Berdowska⁵, B. Rybus-Kalinowska⁶, M. Kalinowski⁷, E. Woźniak-Grygiel¹, R. Bułdak^1
1Physiology, ²Pathomorphology, Medical University of Silesia in Katowice, Zabrze, ³Gastroenterology, Medical University of Silesia in Katowice, Katowice, ⁴Infectious Diseases, Medical University of Silesia in Katowice, Chorzów, ⁵Microbiology and Biotechnology, Jan Długosz University, Czestochowa, ⁶Basic Sciences, Medical University of Silesia in Katowice, Bytom, ⁷First Department of Cardiology, Medical University of Silesia in Katowice, Zabrze, Poland

HEPATITIS C VIRUS INFECTION AND CEREBROVASCULAR DISEASE MORTALITY
M.-H. Lee^1,2, H.-I. Yang¹, C.-L. Jen¹, C.-H. Wang³, Y.-M. Chiou⁴, S.-L. You¹, C.-J. Chen^1,2
1The Genomics Research Center, Academia Sinica, ²Graduate Institute of Epidemiology, College of Public Health National Taiwan University, Taipei, ³Cardinal Tien Hospital, Taipei, ⁴Taichung Veterans General Hospital, Taichung, Taiwan R.O.C.

HEPATITIS C VIRUS INFECTION AND MORTALITY FROM VARIOUS CANCERS: A COMMUNITY-BASED LONG-TERM FOLLOW-UP STUDY
M.-H. Lee^1,2, H.-I. Yang¹, C.-L. Jen¹, S.-L. You¹, C.-A. Sun³, L.-Y. Wang⁴, C.-J. Chen^1,2
1The Genomics Research Center, Academia Sinica, ²Graduate Institute of Epidemiology, College of Public Health National Taiwan University, Taipei, ³School of Public Health, Fu-Jen Catholic University, ⁴School of Public Health, Taipei Medical University, Taipei, Taiwan R.O.C.

EVALUATION OF THE ROUTINE MEDICAL INTERVIEW TO IDENTIFY HEPATITIS C PATIENTS DEVELOPING MAJOR DEPRESSION DURING PEGINTERFERON ALFA-2A PLUS RIBAVIRIN TREATMENT USING THE MAJOR DEPRESSION INVENTORY
P. Leutscher¹, M. Buhl¹, M. Lagging², C. Pedersen³, Å. Alsiö⁴, G. Norkrans⁵, N. Langenland⁶, K. Mørch⁶, M. Färkkillä⁷, P. Bech^8
1Department of Infectious Diseases, Skejby/ Aarhus University Hospital, Aarhus, Denmark, ²Department of Virology and Infectious Diseases, University of Gothenburg, Gothenburg, Sweden, ³Department of Infectious Diseases, Odense University Hospital, Odense, Denmark, ⁴Department of Virology and Infectious Diseases, University of Gothenburg, ⁵Department of Infectious Diseases, Sahlgrenska University Hospital, Gothenburg, Sweden, ⁶Department of Medicine, Haukenland University Hospital, Bergen, Norway, ⁷Department of Gastroenterology, Helsinki University Central Hospital, Helsinki, Finland, ⁸Psychiatric Research Unit, Frederiksborg General Hospital, Hillerød, Denmark

PROSPECTIVE RISK ASSESSMENT FOR HEPATOCELLULAR CARCINOMA DEVELOPMENT IN CHRONIC HEPATITIS C PATIENTS BY TRANSIENT ELASTOGRAPHY
R. Masuzaki, R. Tateishi, H. Yoshida, E. Goto, T. Sato, T. Ohki, J. Imamura, T. Goto, H. Ikeda, S. Shiina, T. Kawabe, M. Omata
Gastroenterology, University of Tokyo, Tokyo, Japan

FOOD INTAKE INCREASES LIVER STIFFNESS IN PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION
I. Mederacke, K. Wursthorn, K. Rifai, M.P. Manns, H. Wedemeyer, M.J. Bahr
Medizinische Hochschule Hannover, Hannover, Germany

HEPATITIS C VIRUS REAPPEARANCE IN HIV-INFECTED PATIENTS WITH SPONTANEOUS HCV-RNA CLEARANCE
L. Peters¹, A. Mocroft², V. Soriano³, J. Rockstroh⁴, N. Kirkby⁵, P. Reiss⁶, C. Katlama⁷, N. Zakharova⁸, R. Flisiak⁹, J. Lundgren^1,5
1Copenhagen HIV Programme - University of Copenhagen, Copenhagen, Denmark, ²University College Medical School, Royal Free Campus, London, UK, ³Hospital Carlos III, Madrid, Spain, ⁴University of Bonn, Bonn, Germany, ⁵Centre for Viral Disease/KMA, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, ⁶Academisch Ziekenhuis bij de Universiteit van Amsterdam, Amsterdam, The Netherlands, ⁷Hopital de la Pitié-Salpêtriére, Paris, France, ⁸St Petersburg AIDS Centre, Saint Petersburg, Russia, ⁹Department of Infectious Diseases, Medical University of Bialystok, Bialystok, Poland

INSULIN RESISTANCE SIGNIFICANTLY CONTRIBUTE TO LIVER STIFFNESS IN NONDIABETIC PATIENTS WITH GENOTYPE 1 HCV INFECTION
S. Petta¹, C. Cammà¹, V. Di Marco¹, V. Calvaruso¹, M. Enea², F. Bronte¹, G. Butera¹, D. Cabibi³, A. Craxì^1
1Cattedra ed U.O.C. di Gastroenterologia ed Epatologia Policlinico di Palermo, ²Dipartimento di Scienze Statistiche e Matematiche “S. Vianelli”, University of Palermo, ³Cattedra di Anatomia Patologica, University of Palermo, Palermo, Italy

FIBROTEST (FT) VALUE INDEPENDENTLY PREDICTS EARLY (EVR) AND SUSTAINED VIROLOGICAL RESPONSE (SVR) IN NON-RESPONDER PATIENTS RE-TREATED WITH PEGYLATED INTERFERON ALFA-2B (PEG-2B) AND RIBAVIRIN IN EPIC³
T. Poynard¹, E.R. Schiff², R. Terg³, R. Moreno-Otero⁴, S.L. Flamm⁵, W. Schmidt⁶, T. Berg⁷, F.L. Goncales⁸, J.E. Heathcote⁹, M. Diago¹⁰, T. McGarrity¹¹, P. Bedossa¹², H. Zhou¹³, P. Mukhopadhyay¹³, L.H. Griffel¹³, M. Burroughs¹³, C.A. Brass¹³, J.K. Albrecht^13
1APHP UPMC, Paris, France, ²University of Miami Center for Liver Diseases, Miami, FL, USA, ³Hospital Municipal de Gastroenterologia Dr Bonorino Udaondo, Buenos Aires, Argentina, ⁴Hospital Universitario de la Princesa, Madrid, Spain, ⁵Northwestern University, Chicago, IL, ⁶VA Medical Center, Iowa City, IA, USA, ⁷Universitätsklinik Charite, Campus Virchow Klinikum, Berlin, Germany, ⁸Hospital das Clinicas da Unicamp Cidade Universitaria Zefirina Vaz, Sao Paulo, Brazil, ⁹University Health Network, Toronto, ON, Canada, ¹⁰Hospital General Universitario de Valencia, Valencia, Spain, ¹¹Milton S Hershey Medical Center, Hershey, PA, USA, ¹²Hopital Beaujon, Clichy, France, ¹³Schering-Plough Research Institute, Kenilworth, NJ, USA

TYPE 1 AND TYPE 2 INTERFERONS AND INTERFERON-INDUCIBLE GENES ARE UPREGULATED IN THE BRAIN OF PATIENTS WITH HEPATITIS C AND SEVERE DEPRESSION
M. Trippler¹, K. Truebner², T. Bajanowski², S. Bein¹, G. Gerken¹, J. Schlaak^1
1Dept. of Gastroenterology and Hepatology, ²Institute of Forensic Medicine, University Hospital of Essen, Essen, Germany

HIGH PREVALENCE OF CHRONIC HEPATITIS C VIRUS (HCV) INFECTION IN A GERMAN METROPOLITAN AREA: A PROSPECTIVE SCREENING ANALYSING 7683 PATIENTS
B. Schlosser¹, D. Domke¹, M. Möckel², M. Biermer¹, B. Fülöp¹, B. Wiedenmann¹, N. Haas³, H. Bail³, C. Müller⁴, R. Tauber⁴, T. Berg^1
1Department for Gastroenterology and Hepatology, ²Department for Cardiology, ³Department for Traumatology, Charite Campus Virchow, ⁴Department for Laboratory Medicine and Pathobiochemistry, Charite, Berlin, Germany

DYNAMIC CHANGE OF LIVER STIFFNESS DURING THE COURSE OF ACUTE HEPATITIS A
Y.S. Seo¹, H. An¹, E.S. Jung¹, B. Keum¹, H.J. Yim¹, Y.T. Jeen¹, H.J. Chun¹, C.D. Kim¹, H.S. Ryu¹, S.H. Um^1,2
1Korea University College of Medicine, ²Liver Cirrhosis Clinical Reserach Center, Seoul, South Korea

EFFECT OF ANTIVIRAL THERAPY ON THE CIRCULATING LEVELS OF CYTOKERATIN-18 FRAGMENTS IN CHRONIC HEPATITIS C
C. Sgier¹, F. Negro², P.J. Malé², D. Moradpour³, R. Malinverni⁴, M. Heim⁵, A. Cerny⁶, B. Müllhaupt⁷, T. Gerlach⁸, J.-F. Dufour^1
1University of Bern, Bern, ²University Hospitals of Geneva, Geneva, ³University Hospital of Lausanne, Lausanne, ⁴Hospital of Neuchâtel, Neuchâtel, ⁵University Hospital of Basel, Basel, ⁶Hospital Moncucco Lugano, Lugano, ⁷University Hospital of Zurich, Zurich, ⁸Hospital of St.Gallen, St. Gallen, Switzerland

INFLUENCE OF HEPATITIS C VIRUS (HCV) INFECTION ON ATHEROSCLEROSIS RISK IN HIV-INFECTED ADULTS
C. Silvain^1,2, M. Wangermez³, P. Sosner⁴, C. Chagneau Deroode³, G. Le Moal^5
1Cytokines and Inflammation Lab, EA 3806, University Hospital Antwerp Poitiers, ²³Hepatology Unit, ⁴Cardiology Unit, ⁵Infectious Diseases Unit, University Hospital Poitiers, Poitiers, France

INACTIVATION OF HEPATITIS C VIRUS BY DISINFECTANTS AND HEAT
S. Ciesek¹, M. Friesland², B. Becker³, H. Wedemeyer¹, M.P. Manns¹, J. Steinmann³, T. Pietschmann², E. Steinmann^2
1Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, ²Department of Experimental Virology, Twincore, and Hannover Medical School, and Helmholtz Centre for Infection Research, Hannover, ³Mikrolab GmbH, Bremen, Germany

INFLUENCE OF GENDER ON VIRAL LOAD ACCORDING TO AGE IN PATIENTS WITH CHRONIC HEPATITIS C: A POSSIBLE EFFECT OF HORMONAL FACTORS
C. Stern¹, R. Moucari¹, A.-C. Cardoso¹, M. Martinot-Peignoux², N. Boyer³, M.-P. Ripault³, P. Bedossa⁴, P. Marcellin^1
1Hepatology Service and INSERM U773-CRB3, ²INSERM U773-CRB3, ³Hepatology Service, ⁴Anatomopathology Service, Hôpital Beaujon, Clichy, France

IS LIVER STIFFNESS ACCURATE TO DEFINE REGRESSION OF CIRRHOSIS IN PATIENTS CURED FROM CHRONIC HEPATITIS C?
P. Sultanik, V. Mallet, A. Vallet-Pichard, H. Fontaine, P. Sogni, S. Pol
Université Paris-Descartes; APHP, Hôpital Cochin, Hépatologie; INSERM U. 567, Paris, France

THE IMPACT OF A MANAGED CARE NETWORK ON ATTENDENCE AT A SPECIALIST HEPATITIS SERVICE AND SUSTAINED VIRAL RESPONSE TO HEPATITIS C TREATMENT
J.M. Tait¹, S. McLeod², J.F. Dillon^1
1Department of Gastroenterology, ²University of Dundee, Ninewells Hospital and Medical School, Dundee, UK

PAIRED BIOPSY COMPARISON OF TWO LIVER FIBROSIS MARKER PANELS (HCV FIBROTEST, HEPASCORE) IN FOLLOWING HISTOLOGICAL RESPONSE TO ANTIVIRAL THERAPY FOR CHRONIC HEPATITIS C (CHC)
A. Thompson, L. Elliott, H. Tillmann, J. McHutchison, K. Patel
Duke Clinical Research Institute, Duke University Medical Centre, Durham, NC, USA

ROLE OF THE CIRRHOSIS RISK SCORE FOR THE PREDICTION OF FIBROSIS PROGRESSION IN HEPATITIS C PATIENTS WITH MINIMAL LIVER DISEASE
P. Pradat¹, E. Trépo², A. Potthoff³, R. Bakshi³, B. Young⁴, R. Lagier⁴, C. Moreno², A. Lemmers², T. Gustot², C. Trépo¹, M. Adler², H. Wedemeyer^3
1Hepatogastroenterology, Hotel-Dieu, Lyon, France, ²Département d'Hepatogastroenterologie, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium, ³Department of Gastroenterology and Hepatology, Medizinische Hochschule, Hannover, Germany, ⁴Celera, Alameda, CA, USA

ASYMPTOMATIC ACUTE/RECENT HCV INFECTION WITH AND WITHOUT BIOCHEMICAL HEPATITIS. NATURAL HISTORY. DISEASE OUTCOME
T. Tsertsvadze^1,2, L. Sharvadze^1,2, A. Abutidze¹, M. Karchava¹, L. Dzigua¹, K. Nelson^3
1AIDS Center, Infectious Diseases, AIDS and Clinical Immunology Research Center, ²Faculty of Medicine, Iv. Javakhishvili Tbilisi State University, Tbilisi, Georgia, ³Epidemiology Department, Johns Hopkins University, Baltimore, MD, USA

LONG-TERM OUTCOME (30 YEARS FOLLOW-UP) IN A SINGLE-SOURCE OUTBREAK OF HEPATITIS C GENOTYPE 1B INFECTION IN GERMANY
V. Weich¹, W. Güthoff², C. John³, M. Wiese⁴, T. Berg^1
1Charité, Virchow Klinikum, Berlin, ²Klinikum Ernst von Bergmann, Potsdam, ³Hepatologische Schwerpunktpraxis, Berlin, ⁴Klinikum St. Georg, Leipzig, Germany

CONTINUED HEAVY TRANSMISSION OF HCV IN A NEEDLE EXCHANGE PROGRAM THAT IS ASSOCIATED WITH MINIMAL TRANMISSION OF HIV. A NINE YEAR LONGITUDINAL COHORT STUDY
A. Widell¹, M. Alanko², L. Flamholc², H. Jacobssen³, V. Molnegren⁴, P. Björkman^2
1Department of Medical Microbiology, ²Department of Infectious Diseases, Malmö University Hospital, Lund University, Malmö, ³Department of Biometric and Statistics, Lund University, Lund, ⁴Department of Medical Microbiology, Malmö University Hospital, Lund University, Malmö, Sweden