The objective was to assess the early adverse reactions after vaccination against influenza with the help of SmithKline Beecham’s Fluarix vaccine in children.
140 children in the age from 3 to 7 were selected to undergo vaccination. These included 74 girls aged average 4.6 and 66 boys aged average 5.1. The vaccination was continued simultaneously during one week and the period of monitoring adverse reactions lasted 7 days. The vaccination was done in accordance with recommendations from the manufacturer, and each child was exam by doctor.
The observed symptoms fell into two categories local and general. The local symptoms included sweeling, reddening and pain in the vaccinated area. 11 children (8%) reported sweeling, 15 children (10.7%) reported reddening, 12 children (8%) reported pain in the vaccinated area. The general symptoms included bad mood and temperature over 37.5. 2 children (1.5%) reported bad mood and 1 child (0.7%) reported temperature over 37.5. none of the monitored children suffered from cheadache, muscle pain and chill.
The low percentage of the early adverse reactions encourages a wider use of vaccines against influenza in children.