Purpose. Investigation in vitro of the magnetic field biological
activity. To determine the role of the indirect electromagnetic stimulations of
the optic nerve in preventing or slow vision loss by enhancing retinal ganglion
cells survival and increasing resistance to injury.
Methods. Retrospective, non-rabdomized comparitive trial.
Electrostimulations with signal - 300 ma, frequence 10-20 Hz and magnetic
influence - 50-60 mcT with frequence 1 Hz. Visual acuity, visual field and
optic nerve electrophysiology
were determined before and after treatment. Courses were repeated every
6 months during 3 years.
Results. Investigations in vitro showed that the influence of magnetic
field with low frequency leads to the normalisation of the intracellular
percent of Ca and activation of Ca connected ferments that restore the
intracellular metabolism. 121 patients (296 eyes with far-advanced glaucoma)
were under the observation. The mean percent of improvement in visual field
were 14,7%, all patients received stabilisation of VF during these 3 years of
follow-up (with IOP no more than 21 HG) and 1-45% of improvement in all cases
just after the course.
Conclusion. Electroma stimulations can be one of the part in optic nerve
neuroprotection. These treatment leads to the activation of the alive fibrills,
functional change and restoration of the parabiotic nerve fibrills and
metabolism in the ganglion cells.