PURPOSE. To investigate
the role of antibody level to type of collagen I and III in serum on the
success of filtration surgery.
METHODS. To examined antibody level to type of collagen I and III in
serum by sandwich ELISE of 53 patients with primary open-angle glaucoma (POAG)
- 36 eyes and secondary uveal glaucoma - 17 eyes before filtration surgery and
past week after it.
RESULTS. We study antibodies to type of collagen I in serum patients
with POAG in 33% and secondary uveal glaucoma in 50% case and antibodies to type
of collagen III in serum patients with POAG in 67% and secondary uveal glaucoma
in 50% case before filtration surgery. We followed up all patients (53 eyes)
operated on for glaucoma 12 months. We detected excessive scarring during
postoperation period, when antibodies to type of collagen I and III were not
determine in serum before operation.
CONCLUSION. Antibodies to type of collagen I and III in serum may be
controlled before filtration glaucoma surgery as a testing of filtration
glaucoma surgery result.