To investigate the effects of apraclonidine and apraclonidine combined
with b-blocker (selective and nonselective ) on the diameter of retinal vessels.
Patient and Methods: 20 eyes of 10 patients were treated with apraclonidine (Group 1), 20 eyes of 10
patients were treated with a combination of apraclonidine and
betaxolol hydrocloride (Group 2) and 20 eyes 10 patients were treated
with a combination of aproclonidine and timolol maleate (Group 3). The diameters of retinal
vessels were measured by taking red free fundus images with Topcon IMAGInet
TRCIA before and one week, one month and three months after administration of
drugs in three groups.
Results: There was no significant difference in diameters of retinal
vessels before and one week, one month and three months after administration of
drugs .
Conclusion: Application of apraclonidine and apraclonidine combined with
b- blockers do not effect the diameters of retinal vessels and lower the
intraocular pressure.