COMPARISON OF VISCOCANALOSTOMY AND TRABECULECTOMY AS PRIMARY PROCEDURE IN UNCONTROLLED OPEN ANGLE GLAUCOMA - A PROSPECTIVE RANDOMIZED STUDY

C.  Lüke, T. S. Dietlein, P. C. Jacobi, W. Konen and G. K. Krieglstein

Zentrum für Augenheilkunde, Universität Köln, Germany

Purpose: To assess the efficacy and postoperative complications of viscocanalostomy versus trabeculectomy.

Methods: Fourty eyes of fourty patients with medically uncontrolled open-angle glaucoma were randomized either to the viscocanalostomy or to the trabeculectomy group of the trial. Viscocanalostomy was performed according to Stegmann`s technique using high molecular weight sodium hyaluronate to fill the ostia of Schlemms canal. For trabeculectomy a modified Cairns-trabeculectomy was performed. Examinations were performed before surgery and postoperatively daily for one week. Follow-up visits were applied 1,6 and 12 months after surgery.

Results: The mean preoperative intraocular pressure (IOP) was 26.7 (SD 6.3) mmHg for all patients enrolled. The mean postoperative IOP was 10.5 (SD 6.60) for the trabeculectomy group and 17.1 (SD 7.0) for the viscocanalostomy group, respectively. The postoperative IOP-difference between the two groups was statistically significant (p = 0.007). The success rate, defined as an IOP lower than 21 mmHg without medication, was 60 % in the trabeculectomy group and 15 % in the viscocanalostomy group at 12 months postoperatively (p = 0.004). The number of postoperative complications was lower in the viscocanalostomy group.

Conclusions: In eyes with open angle glaucoma, viscocanalostomy, is less effective in reducing postoperative IOP than the standard filtering procedure. However, the risk profile, appears to be more favorable in the eyes treated with viscocanalostomy.