Objective: To compare the results of combined trabeculectomy with
phacoemulsification and posterior chamber intraocular implantation (IOL) to
those of trabeculectomy alone, with Mitomycin C (MMC) application in all cases.
Design: A retrospective comparative study of consecutive patients.
Participants: One hundred and two eyes of 90 pateints were studied in
the combined procedure group, and 33 eyes of 30 patients in the trabeculectomy
group.
Main Outcome Measures: Mean pre- and postoperative intraocular pressure
(IOP), number of anti-glaucomatous medications used pre- and postoperative,
functioning of the filtering bleb, and complications.
Results: Both groups showed a significant decrease in IOP, combined
group, 6.755.7 mmHg (meanSD), p=0.0001; trabeculectomy group, 11.757.9 mmHg
(meanSD), p=0.0001. The IOP decrease was significantly larger in the
trabeculectomy group (p=0.0001). Postoperativly, the two groups showed similar
significant reductions in the number of anti-glaucomtous medications used
(combined group, o.821.0 compared with 2/650.84 preopratively, p=0.0001;
trabeculectomy group, 0.761.2 compared with 2.70.95 preoperatively, p=0.0001).
There were no cases of bleb leakage in the combined group and two cases (6%) in
the trabeculectomy group.
Conclusion: Except for s significant larger postoperative IOP decrease
in the patients who underwent trabeculectomy alone, the results of the combined
procedure of phacoemulsification, posterior chamber IOL implantation and
trbeculectomy with MMC application were as good as those of trabeculectomy
alone with MMC.