STUDY OF OCULAR HYPERTENSION WITH GDX AND BLUE ON YELLOW PERIMETRY

G. T. Georgopoulos, L. E. Patsea, M. Alexiou, J. Vergados, D. G. Andreanos and G. P. Theodossiadis

Department of Glaucoma, Department of Ophthalmology, Medical School, Athens University, Greece

Introduction: Laser polarimetry measurements (GDx) were compared to the results of Humphrey blue-on-yellow perimetry (BY) in patients with ocular hypertension (OHT) and normal white on white (WW) automated perimetry.

Methods: 84 eyes of 42 patients with OHT examined with GDx and automated visual field (VF) testing (Humprey analyzer, program 30-2) using WW and BY perimetry. We calculated the correlation coefficients of the VF indices (GHT, MD, PSD, SF, and CPSD) on Humphrey BY perimetry and various GDx retardation parameters. We also compared the agreement of the location of visual field defects with changes of the nerve fiber layer thickness.

Results: 14 eyes showed visual field defects in BY perimetry. The nerve fiber layer thickness in superior, nasal and inferior quadrants was significantly lower in all eyes with visual field defects in BY perimetry (p<0.01). The GDx parameters superior average, superior integral, average thickness and ellipse average were more correlated with MD and PSD in BY perimetry. Localization of nerve fiber defects corresponded to the localization of the BY visual field defects in 11 of the 14 eyes.

Conclusion: Quantitative measurements of the retinal nerve fiber layer using scanning laser polarimetry were correlated with BY visual field data in ocular hypertensive patients allowing for distinguishing cases where glaucoma is more likely to develop.