Glaucoma surgery in patients with severely endangered visual field center raises the problem of potential snuff out phenomenon. To reduce this risc surgery may be performed in general anesthesia. We performed trabeculectomy in 24 eyes with severely endangered visual field center, using combined 4 percent lidocain drop anesthesia and 1 percent lidocain intracameral anesthesia. With the intention to keep the surgical time as short as possible, the adjunctive mitomycin C was subconjunctivally injected 7 to 10 minutes prior to surgery. We injected 50 to 100 microliters of 20 to 100 microgram per microliter mitomycin C, that is an applied dose of 1 to 10 microgram mitomycin C. We report on difficulties performing trabeculectomy in a mobile eye. We also report the frequency of patients suffering intraoperative pain at the time of iridectomy or at any time. We furthermore evaluated the postoperative success and complication rates. The postoperative complications included hypotony, flat chamber, choroidal effusion, surgical failure and filtering bleb encapsulation. We also classified the filtering bleb appearance with special interest in the frequency of avascular and thin cystic blebs. Concluding, drop anesthesia combined with intracameral anesthesia is a feasible technical alternative to general anethesia in patients, where parabulbar or retrobulbar injection may be a risk. However, the closure of the scleral flap may be considerably more difficult especially in poorly exposed eyes. This may result in an increased risk of postoperative hypotony and associated complications.