THE LOCUS COERULEUS MODELING INFLUENCE ON THE STRESS-GENERATED OPHTALMOHYPERTENSION

A.A.V. Myagkov, I.R. Phathyhov and S.V. Zubcova

Medical Academi, Izshevsk, Russia

The central nervous system, especially hypothalamus, takes the important place in ophtalmotonus regulation.  The hypothalamus in one of the stress activating brain system. The electrical and chemical hypothalamus ventromedial nucleus (HVMN) leads to the rapid increasing of the ophtalmotonus. Locus coeruleus (LC) has the neurochemical specificity. It gives the multiple connections with hypothalamus and forms numerous collaterals with substantia grisea centralis, cortex, thalamus, corpus amygdaloideum and others. Due to this, we studied the LC influence on the ophtalmotonus state and its affect on the ophtalmohypertension in the chronic emotion stress conditions which has been produced by the HVMN electrostimulation. During the HVMN electrostimulation we recicved the stable ophtalmohypertension. The ophtalmohypertension  was caused by the humor aquosus outrun facility ratio reducing and by the increasing of its production. The combination of the HVMN and LC electrostimulation doesn’t cause the ophtalmotonus increasing because the humor aquosus outrun facility ratio run up proportioned to the volume humor aquosus minute increasing.

So, the combination of the HVMN and LC electrostimulation causes the reducing to zero of the ophtalmohypertensive affect of the lastone. E-mail: optica@udm.ru