SCANNING RETINAL THICKNESS ANALYSIS: A SENSITIVE METHOD FOR THE EARLY DIAGNOSIS OF THE OPEN ANGLE GLAUCOMA

L. Arrico, A. Mollicone, S. Donati, R. Losciale, E.M. De Santis and       A. Missiroli

Istiute of Ophthalmology, University of Rome "La Sapienza", Rome, Italy

INTRODUCTION The retinal thickness analysis is a method that can measure the posterior pole retinal thickness and its changes due to glaucomatous damage.

MATERIAL AND METHODS We recruited two groups of patients:1) 35 patients (70 eyes)with POAG 2) 20 patients (40 eyes)without therapy and both with borderline IOP .Both groups didn't show any visual field defects.The follow-up was of three years.We analysed the retinal thickness of the posterior pole with retinal thickness analyzer (RTA). RESULTS In the POAG group only 5,5% of the eyes showed a significant reduction of the posterior pole average (PPAV).Wile the 40% presented a significant alteration of the posterior pole temporal/nasal asymmetry(PPTNA)and the 35% a significant alteration of peri-foveal superior/inferior and temporal/nasal asymmetry (PFSIA and PFTNA).In the borderline group with no significant reduction of PPAV the 31% of the eyes showed an alteration of PPTNA, the 31,2% an alteration of PFSIA and the 18% an alteration of PFTNA. CONCLUSIONS In the litterature has been demostrated that there is a correlation between the visual field asymmetry and the variation from the normal retinal thickness. In our study the two groups didn't present (as expression of glaucoma damage) such asymmetry of the visual field and neither in 40% of POAG eyes in wich we found an alterated PPTNA.This could be an indicator of early glaucoma injury unrevealed by a visual field testing but detected by thickness analysis.a longitudinal follow-up will be done to test this hypotesis.