PURPOSE: Investigation of the most effective methods of introduction of neurotrophic and vessel dilated medicines in children with innate compensated glaucoma in post operative period aimed to improve the functional condition of the optic nerve.
METHODS: Two groups of children of 6 months - 3 years old were studied. In the 1st group (11 children, 14 eyes) neurotrophic and vessel dilated medicines were introduced in the form of the retro-bulbar injections (0,5 ml once a day during 10 days). In the 2nd group (8 children, 9 eyes) the same medicines were introduced through the system of irrigation in the thenon or the retro-bulbar space (0,3 ml 5-6 times a day during 10 days). All patients were examined before and after treatment with electrophysiological methods. Visual evoked potential's P100 was analysed.
RESULTS: In the 2nd group the average P100's amplitude / latency changes was equal to 2,4-3,3 mkV / 2,5-3,9 ms and in the 1st group - 1,9-2,3 mkV / 2,2-3,1 ms.
CONCLUSION: The neurotrophic effect is more expressed in intensive supply of the medicines into the thenon or the retro-bulbar space.