PURPOSE: To develop the System of connected, pathogenically grounded methods of central visual field (CPVF) examinations for evaluating early glaucoma manifestations, the precise treatment control and dynamics of ones when low vision.
METHODS: Color Campimetry (PC-based “Ocular” program) system for 21 degrees VF investigation supporting Static/Flicker Incremental Luminance Sensitivity Thresholds (LST), Directional Motion Sensitivity Algorithm (DMSA), with achromatic/colored stimuli/backgrounds were used in 296 Glaucoma Suspects and 438 Glaucoma I-IV patients plus Humphrey, Perimat, Kowa Automated Perimetry (AP).
RESULTS: In Glaucoma Suspects the following changes in CPVF were detected (P<0.01): 11% by Red/Grey Stimulus/Background LST (Test1); 18% by Test1 plus Red/Grey Flicker LST (Test2); 41% by Test1 plus Blue/Yellow LST (Test3); 59% by Test3 plus Blue/Yellow DMSA (Test4); 65% by Test2 plus Test4 (Test5). In Glaucoma I the Tests 1-5 showed 19%, 29%, 51%, 64%, 76% respectively. In Glaucoma II the Tests 1-3 revealed 76%, 91%, 98%.
CONCLUSIONS: The reliability, differential sensitivity and resolution of the CPVF investigations are improved using the System of methods; individual dynamics and pathophysiological mechanisms in optic nerve and retina are believed to be clarified.