TOPICS
OF LECTURES, WORKSHOPS AND SYMPOSIA
 |
A.
BASIC
ASPECTS OF GnRH ANALOGUES (AGONISTS AND ANTAGONISTS)
- Design, Synthesis and Clinical Pharmacology of effective and safe
antagonists of GnRH
- Developments of GnRH antagonists and update
- Primate studies on GnRH antagonists
- Clinical studies with GnRH antagonists
- GnRH analogues of the future
- Intracellular LH releasing mechanism by GnRH analogues
- GnRH receptor and signal transduction in normal and malignant tissues:
(Normal Pituitary,
Normal Gonads, Normal Breast, Myoma, Prostate Cancer, Ovarian,
Endometrial, Breast Cancer)
- Effects of GnRH antagonists on spermatogenesis
- Direct Effects of antagonists on Granulosa cells
- Comparison of GnRH agonists and antagonists in experimental animal
models
- Controlled suppression of gonadal steroids with GnRH agonists or
antagonists
- Mechanism(s) of local effects of GnRH analogues and GnRH like-peptides
and their possible application in clinical practice
- Differences of GnRH analogues - fact or fiction
- Central and peripheral effects of different analogues
- Clinical impact of different analogues due to their chemical nature
and delivery system
- New Indications for the use of GnRH Analogues
- Pharmacokinetic characteristics of GnRH Antagonist
- Pharmacodynamics of GnRH Analogues (Agonists and Antagonists)
- Bio-Pharmaceutical Studies (Agonists and Antagonists) |
B.
GnRH ANALOGUES IN PROSTATE CANCER
- Epidemiology
- Scopes and limits of endocrine management of prostatic cancer
- Combination of endocrine and non-endocrine treatment of prostate
cancer
- Neo and Adjuvant Treatment of LHRH analogues in early prostate cancer
- Combination Therapy of LHRH analogues with chemotherapy in hormone
refractory PCA
- Intermittent Therapy for prostate cancer
- Total versus partial androgen blockade in advanced prostate cancer
- Results of treatment of metastatic cancer using GnRH analogues
- Development of LHRH antagonists in prostate cancer
- Conservative management of benign prostate hypertrophy: future aspects
- New perspectives in the treatment of prostate cancer
- Treatment of hormone-refractory prostate cancer |
C.
GnRH ANALOGUES IN REPRODUCTION
- Modern concepts in ovarian stimulation
- The era of recombinant Gonadotropin
- Mechanisms of actions and perspectives of the use of GnRH antagonists
in women
- Clinical application of GnRH analogues in reproduction
- Use of GnRH analogues in the overall management of polycystic ovarian
disease
- Do GnRH analogues represent an effective adjunctive treatment of
infertility in polycystic ovarian disease?
- Use of GnRH analogues for in-vitro fertilization
- Will GnRH analogues help in diagnosis prevention and treatment of
functional ovarian cysts?
- Will application of GnRH analogues enable classification of stages and
treatment of some types of premature ovarian failure?
- Results of GnRH antagonists in IVF
- Results of Dose-finding of GnRH antagonists
- Studies of Multiple Dose protocols of GnRH antagonists
- Optimization of GnRH antagonists protocol
- Studies of Single Dose protocols of GnRH antagonists
- Use of GnRH agonists for triggering ovulation in GnRH antagonists
protocols
- Minimization of OHSS in GnRH antagonist protocols
- Results and follow-up of children born after GnRH antagonist therapy
- The clinical value of long acting GnRH analogues (agonists and
antagonists), in the treatment of uterine fibroids
- The use of GnRH analogues for dysfunctional uterine bleeding |
D.
GnRH ANALOGUES IN
ENDOMETRIOSIS
- Is there a role for GnRH antagonists in the management of
endometriosis
- Long-term results with GnRH analogues in the treatment of
endometriosis
- Early treatment of GnRH analogues in the treatment of endometriosis
- GnRH analogues in the management of Pelvic Pain
- Management of active and inactive Endometriosis |
E.
GnRH AGONISTS IN
OVARIAN, BREAST AND PROSTATE
CANCERS
- Epidemiology
- Scopes and limits of endocrine management of prostate cancer
- The use of GnRH agonists and antagonists in the management of ovarian
cancer
- The use of GnRH agonists and antagonists in the management of breast
cancer
- The application of GnRH analogues in the management of endometrial
cancer
- The use of GnRH agonists and antagonists in the management of other
cancers
- The combined use of GnRH analogues and somatostatin in the management
of cancer
- The combination use of GnRH analogues and other therapeutic measures
in the management of cancer
- The potential diagnostic application of GnRH antagonists in
mammography |
F.
GnRH ANALOGUES IN
CONTRACEPTION
- Animal models for testing GnRH analogues in female reproduction
- Peptide contraception by inhibition of ovulation using GnRH analogues
- Animal models for testing GnRH analogues in male reproduction
- The use of GnRH analogues in male contraception |
| G.
GnRH ANALOGUES IN MALE
INDICATION |
H.
SAFETY
- Bone density changes associated with GnRH analogues
- Management of post-marketing surveillance following short and
long-term use of GnRH analogues
- Recovery of hormone secretion following long-term GnRH analogue
treatment
- The long-term effect on fertility and bone mass following chronic long
lasting GnRH analogues treatment in children
- Safety of short and long-term treatment with GnRH analogues
- Safety of GnRH antagonists for mother and child |
