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SCIENTIFIC PROGRAM (Preliminary)

THURSDAY, FEBRUARY 19, 2004
 
08:45 - 09:00 OPENING REMARKS
Uri Seligsohn
Seminar Chairman
 
09:00 - 10:30 SESSION I
“EXTRA CURRICULAR” FUNCTION OF COAGULATION COMPONENTS
Chairperson: Aida Inbal
09:00 Activated protein C cellular protective effect
John Griffin, U.S.A.
09:30 Regulation of coagulation and inflammation by components of the protein C anticoagulant pathway
Charles Esmon, U.S.A.
10:00 Proangiogenic effects of factor XIIIa
Aida Inbal and Rima Dardik, Israel
10:30 Coffee break
 
11:00 - 12:30 SESSION II
MECHANISMS OF COAGULATION
Chairperson: Martin Ellis
11:00 A new look into the mechanisms of haemostasis
Dougald Monroe, U.S.A.
11:30  Coagulation factors: Can we improve on nature?
Gil White, U.S.A.
12:00 Antiphospholipid antibody-mediated thrombosis:
From syndrome to mechanisms
Jacob Rand, U.S.A.
12:30  Lunch and visit the exhibition
 
14:00 - 15:30 SESSION III
TISSUE FACTOR PATHWAY AND r-FACTOR VIIa

Chairperson: Gili Kenet
14:00 Blood borne tissue factor
Yale Nemerson, U.S.A.
14:30 The regulation of tissue factor activity expression in
whole blood
Bjarne Osterud, Norway
15:00 Use of r-factor VIIa in uncontrolled bleeding
Uri Martinowitz, Israel
15:30 Coffee break
 
16:00 - 17:30 SESSION IV
FACTOR XI, TAFI, COMBINED DEFICIENCY OF FACTORS V AND VIII
Chairperson: Ron Hoffman
16:00 Molecular genetic aspects of factor XI deficiency
Ariella Zivelin, Israel
16:30 TAFI: A link between coagulation and fibrinolysis.
Insights into its possible physiological function
Bonno Bouma, U.S.A.
17:00 Combined deficiency of factors V and VIII: Biologic insight from the study of human disease
David Ginsburg, U.S.A.
 
FRIDAY, FEBRUARY 20, 2004
 
08:30 - 10:30 SESSION V
PLATELET VESSEL WALL INTERACTION AND DISEASES
Chairperson: Varda Deutsch
08:30 Beta 3 integrins in blood and vascular disease
Barry Coller, U.S.A.
09:00 Platelet collagen receptor defects in mice and man
Peter Newman, U.S.A.
09:30 Naturally occurring mutations causing Glanzmann thrombasthenia: Lessons regarding structure -
function relationships
Nurit Rosenberg, Israel
10:00 Extracellular disulfide exchange - a novel control mechanism regulating platelet function
Judith Lahav, Israel
10:30 Coffee break
 
11:00 - 12:30 SESSION VI
VENOUS THROMBOSIS
Chairperson: Aharon Lubetzky
11:00 New antithrombolic agents
Michel Samama, France
11:30 Inherited thrombophilias: The past, the present and
the future
Pier Mannucci, Italy
12:00 Thrombophilias during pregnancy
Benjamin Brenner, Israel
12:30 Lunch and visit of the exhibition
 
14:00 - 15:30 SESSION VII
MEASURING HAEMOSTASIS
Chairperson: Aaron Tomer
14:00 Thrombin generation
Peter Giessen, The Netherlands
14:30 Measuring Haemostasis
David Varon, Israel
15:00 Understanding thrombosis and Haemostasis
through “experiments of nature”
Uri Seligsohn, Israel